Digital twins in healthcare: a comprehensive review and future directions. - Hamid Khoshfekr Rudsari; Becky Tseng; Hongxu Zhu; Lulu Song; Chunhui Gu; Abhishikta Roy; Ehsan Irajizad; Joseph Butner; James P. Long; Kim-Anh Do (Frontiers Digit. Health, 2025)