Methods to modernize a multimedia, web-based reproductive health education intervention for individuals with sickle cell disease or trait using virtual human narration and user-centered design. - Alexandre Gomes de Siqueira; Gina M. Gehling; Aravind Subramanian; Anna Le; Rishabh Garg; Abigail R. Islam; Destiny Gordon; Tyra Reed; Amelia Greenlee; Guettchina Telisnor; Andrea Rangel; Candice J. Adams-Mitchell; et al. (Health Informatics J., 2025)