Christoph Lange

According to our database, Christoph Lange authored at least 15 papers between 2006 and 2024.

Collaborative distances:

• Dijkstra number of five.
• Erdős number of four.

2024

Fast computation of the eigensystem of genomic similarity matrices.

Georg Hahn, Sharon Marie Lutz, Julian Hecker, Dmitry Prokopenko, Michael H. Cho, Edwin K. Silverman, Scott T. Weiss, Christoph Lange

BMC Bioinform., December, 2024

2023

A comparison between similarity matrices for principal component analysis to assess population stratification in sequenced genetic data sets.

Sanghun Lee, Georg Hahn, Julian Hecker, Sharon Marie Lutz, Kristina Mullin, Winston Hide, Lars Bertram, Dawn L. Demeo, Rudolph E. Tanzi, Christoph Lange, Dmitry Prokopenko

Briefings Bioinform., January, 2023

2022

Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest.

Georg Hahn, Sanghun Lee, Dmitry Prokopenko, Jonathan Abraham, Tanya Novak, Julian Hecker, Michael H. Cho, Surender Khurana, Lindsey R. Baden, Adrienne G. Randolph, Scott T. Weiss, Christoph Lange

BMC Bioinform., December, 2022

2021

A fast and efficient smoothing approach to Lasso regression and an application in statistical genetics: polygenic risk scores for chronic obstructive pulmonary disease (COPD).

Georg Hahn, Sharon Marie Lutz, Nilanjana Laha, Michael H. Cho, Edwin K. Silverman, Christoph Lange

Stat. Comput., 2021

A unifying framework for rare variant association testing in family-based designs, including higher criticism approaches, SKATs, and burden tests.

Julian Hecker, F. William Townes, Priyadarshini Kachroo, Cecelia A. Laurie, Jessica Lasky-Su, John Ziniti, Michael H. Cho, Scott T. Weiss, Nan M. Laird, Christoph Lange

Bioinform., 2021

2019

Local and Global Stratification Analysis in Whole Genome Sequencing (WGS) Studies Using LocStra.

Georg Hahn, Sharon Marie Lutz, Julian Hecker, Dmitry Prokopenko, Christoph Lange

Proceedings of the Computational Advances in Bio and Medical Sciences, 2019

2017

Identification of genetic outliers due to sub-structure and cryptic relationships.

Daniel Schlauch, Heide Loehlein Fier, Christoph Lange

Bioinform., 2017

2016

Utilizing the Jaccard index to reveal population stratification in sequencing data: a simulation study and an application to the 1000 Genomes Project.

Dmitry Prokopenko, Julian Hecker, Edwin K. Silverman, Marcello Pagano, Markus M. Nöthen, Christian Dina, Christoph Lange, Heide Loehlein Fier

Bioinform., 2016

2014

On the simultaneous association analysis of large genomic regions: a massive multi-locus association test.

Dandi Qiao, Michael H. Cho, Heide Loehlein Fier, Per S. Bakke, Amund Gulsvik, Edwin K. Silverman, Christoph Lange

Bioinform., 2014

FARVAT: a family-based rare variant association test.

Sungkyoung Choi, Sungyoung Lee, Sven Cichon, Markus M. Nöthen, Christoph Lange, Taesung Park, Sungho Won

Bioinform., 2014

2012

Handling the data management needs of high-throughput sequencing data: SpeedGene, a compression algorithm for the efficient storage of genetic data.

Dandi Qiao, Wai-Ki Yip, Christoph Lange

BMC Bioinform., 2012

'Location, Location, Location': a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate.

Heide Loehlein Fier, Sungho Won, Dmitry Prokopenko, Taofik AlChawa, Kerstin U. Ludwig, Rolf Fimmers, Edwin K. Silverman, Marcello Pagano, Elisabeth Mangold, Christoph Lange

Bioinform., 2012

2011

Quantitative trait prediction based on genetic marker-array data, a simulation study.

Wai-Ki Yip, Christoph Lange

Bioinform., 2011

2008

On the frequency of copy number variants.

Iuliana Ionita-Laza, Nan M. Laird, Benjamin A. Raby, Scott T. Weiss, Christoph Lange

Bioinform., 2008

2006

P²BAT: a massive parallel implementation of PBAT for genome-wide association studies in R.

Thomas Hoffmann, Christoph Lange

Bioinform., 2006