S-SPAM; a search method for Spatio-temporal Patterns of Mutations. Study case: A variability analysis in the spike protein of SARS-CoV-2. - Francisco Hernández-Cabrera; Cynthia Elizabeth Castillo-Silva; José Roberto Cantú-González; Francisco Javier Almaguer-Martínez (J. Comput. Appl. Math., 2024)