Development of a simulation algorithm for mammographic imaging based on Monte Carlo methods - George M. Spyrou (2001)

Study on Preprocessing and Classifying Mass Spectral Raw Data Concerning Human Normal and Disease Cases. - Xenofon E. Floros; George M. Spyrou; Konstantinos N. Vougas; George T. Tsangaris; Konstantina S. Nikita (ISBMDA, 2006)

Evaluation of a Breast Cancer Computer Aided Diagnosis System. - Antonis Frigas; Smaragda Kapsimalakou; George M. Spyrou; Konstantinos Koufopoulos; Stamatios Vassilaros; Aikaterini Chatzimichael; John Mantas; Panos A. Ligomenides (MIE, 2006)

"Hippocrates-mst": a prototype for computer-aided microcalcification analysis and risk assessment for breast cancer. - George M. Spyrou; Smaragda Kapsimalakou; Antonis Frigas; Konstantinos Koufopoulos; Stamatios Vassilaros; Panos A. Ligomenides (Medical Biol. Eng. Comput., 2006)

A Survey of the Availability of Primary Bioinformatics Web Resources. - Trias Thireou; George M. Spyrou; Vassilis Atlamazoglou (Genom. Proteom. Bioinform., 2007)

A high throughput approach to keep alive a web-based database system for multiple search among published bioinformatics tools and databases. - Vassilis Atlamazoglou; Trias Thireou; Anastasia Alexandridou; George M. Spyrou (BIBE, 2008)

Protein similarity networks and Genetic Algorithm driven feature selection for fold recognition. - Ioannis K. Valavanis; George M. Spyrou; Konstantina S. Nikita (BIBE, 2008)

Peptide Finder: mapping measured molecular masses to peptides and proteins. - Anastasia Alexandridou; George T. Tsangaris; Konstantinos N. Vougas; Konstantina S. Nikita; George M. Spyrou (Bioinform., 2008)

Design of a 'Smart' Patient Record System for Mammography Patients. - Antonis Frigas; George M. Spyrou; Argyro Antaraki; Elisabeth Patiraki; Konstantinos Koufopoulos; John Mantas; Panos A. Ligomenides (MIE, 2009)

UniMaP: finding unique mass and peptide signatures in the human proteome. - Anastasia Alexandridou; George T. Tsangaris; Konstantinos N. Vougas; Konstantina S. Nikita; George M. Spyrou (Bioinform., 2009)

Downgrading BIRADS 3 to BIRADS 2 category using a computer-aided microcalcification analysis and risk assessment system for early breast cancer. - Georgia Giannakopoulou; George M. Spyrou; Argyro Antaraki; Ioannis Andreadis; Dimitra Koulocheri; Flora Zagouri; Afroditi Nonni; George M. Filippakis; Konstantina S. Nikita; Panos A. Ligomenides; George C. Zografos (Comput. Biol. Medicine, 2010)

PET image reconstruction: A stopping rule for the MLEM algorithm based on properties of the updating coefficients. - Anastasios Gaitanis; George Kontaxakis; George M. Spyrou; George Panayiotakis 001; George Tzanakos (Comput. Medical Imaging Graph., 2010)

Studying the properties of the updating coefficients in the OSEM algorithm for iterative image reconstruction in PET. - Anastasios Gaitanis; George Kontaxakis; George M. Spyrou; George Panayiotakis 001; George Tzanakos (Comput. Methods Programs Biomed., 2010)

A similarity network approach for the analysis and comparison of protein sequence/structure sets. - Ioannis K. Valavanis; George M. Spyrou; Konstantina S. Nikita (J. Biomed. Informatics, 2010)

PepServe: a web server for peptide analysis, clustering and visualization. - Anastasia Alexandridou; Nikolas Dovrolis; George T. Tsangaris; Konstantina S. Nikita; George M. Spyrou (Nucleic Acids Res., 2011)

Investigating the Minimum Required Number of Genes for the Classification of Neuromuscular Disease Microarray Data. - Argiris Sakellariou; Despina Sanoudou; George M. Spyrou (IEEE Trans. Inf. Technol. Biomed., 2011)

e-Prolipsis: A web based risk estimation platform to support and register breast cancer diagnosis in Greece. - Alexandros C. Dimopoulos; John Lakoumentas; Argyro Antaraki; Antonis Frigas; Emmanouil K. Ikonomakis; Marinos Sampson; Anastasios Tagaris; Aikaterini Liakou; Emmanouil Athanasiadis; George M. Spyrou; Panos A. Ligomenides (BIBE, 2012)

Enhancing the effectiveness of virtual screening by using the ChemBioServer: Application to the discovery of PI3Kα inhibitors. - Paraskevi Gkeka; Emmanouil Athanasiadis; George M. Spyrou; Zoe Cournia (BIBE, 2012)

Clustering microarray data using fuzzy clustering with viewpoints. - Katerina N. Karayianni; George M. Spyrou; Konstantina S. Nikita (BIBE, 2012)

ChemBioServer: a web-based pipeline for filtering, clustering and visualization of chemical compounds used in drug discovery. - Emmanouil Athanasiadis; Zoe Cournia; George M. Spyrou (Bioinform., 2012)

Combining multiple hypothesis testing and affinity propagation clustering leads to accurate, robust and sample size independent classification on gene expression data. - Argiris Sakellariou; Despina Sanoudou; George M. Spyrou (BMC Bioinform., 2012)

Generation of clustered microcalcifications' atlases for benign and malignant cases. - Ioannis Andreadis; George M. Spyrou; Panos A. Ligomenides; Konstantina S. Nikita (BIBE, 2013)

Variations on breast density and subtlety of the findings require different computational intelligence pipelines for the diagnosis of clustered microcalcifications. - Ioannis Andreadis; George M. Spyrou; Panos A. Ligomenides; Konstantina S. Nikita (BIBE, 2013)

Performance evaluation of clustering algorithms on microcalcifications as mammography findings. - Emmanouil K. Ikonomakis; George M. Spyrou; Panos A. Ligomenides; Michael N. Vrahatis (BIBE, 2013)

Developing a simulator for multispectral optoacoustic tomography. - Efthymios Maneas; Stratis Tzoumas; Vasilis Ntziachristos; George M. Spyrou (BIBE, 2013)

Modeling of solitary pulmonary nodules in PET/CT images using Monte Carlo methods. - George M. Tzanoukos; Anastasios Gaitanis; Alexandros Georgakopoulos; Achilleas Chatziioannou; Sofia Chatziioannou; George M. Spyrou (BIBE, 2013)

BiDaS: a web-based Monte Carlo BioData Simulator based on sequence/feature characteristics. - Maria D. Paraskevopoulou; Ioannis S. Vlachos; Emmanouil Athanasiadis; George M. Spyrou (Nucleic Acids Res., 2013)

A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools. - Emmanouil Athanasiadis; Kyriaki Antonopoulou; Foteini Chatzinasiou; Christina M. Lill; Marilena M. Bourdakou; Argiris Sakellariou; Katerina Kypreou; Irene Stefanaki; Evangelos Evangelou; John P. A. Ioannidis; Lars Bertram; Alexander J. Stratigos; et al. (Database J. Biol. Databases Curation, 2014)

GeneStoryTeller: a mobile app for quick and comprehensive information retrieval of human genes. - Stergiani V. Eleftheriou; Marilena M. Bourdakou; Emmanouil I. Athanasiadis; George M. Spyrou (Database J. Biol. Databases Curation, 2015)

mAPKL: R/ Bioconductor package for detecting gene exemplars and revealing their characteristics. - Argiris Sakellariou; George M. Spyrou (BMC Bioinform., 2015)

ZoomOut: Analyzing Multiple Networks as Single Nodes. - Emmanouil I. Athanasiadis; Marilena M. Bourdakou; George M. Spyrou (IEEE ACM Trans. Comput. Biol. Bioinform., 2015)

A CAD$_{ bf x}$ Scheme for Mammography Empowered With Topological Information From Clustered Microcalcifications' Atlases. - Ioannis Andreadis; George M. Spyrou; Konstantina S. Nikita (IEEE J. Biomed. Health Informatics, 2015)

Bioinformatics methods in drug repurposing for Alzheimer's disease. - John C. Siavelis; Marilena M. Bourdakou; Emmanouil I. Athanasiadis; George M. Spyrou; Konstantina S. Nikita (Briefings Bioinform., 2016)

SPNsim: A database of simulated solitary pulmonary nodule PET/CT images facilitating computer aided diagnosis. - George M. Tzanoukos; Erast Athanasiadis; Anastasios Gaitanis; Alexandros Georgakopoulos; Achilleas Chatziioannou; Sofia Chatziioannou; George M. Spyrou (J. Biomed. Informatics, 2016)

Informed walks: whispering hints to gene hunters inside networks' jungle. - Marilena M. Bourdakou; George M. Spyrou (BMC Syst. Biol., 2017)

Automatic cumulative sums contour detection of FBP-reconstructed multi-object nuclear medicine images. - Nicholas E. Protonotarios; George M. Spyrou; George A. Kastis (Comput. Biol. Medicine, 2017)

D-Map: Random Walking on Gene Network Inference Maps Towards differential Avenue Discovery. - Emmanouil Athanasiadis; Marilena M. Bourdakou; George M. Spyrou (IEEE ACM Trans. Comput. Biol. Bioinform., 2017)

Computational Identification of Metabolites for Pathways Related to Huntington's Disease. - Christiana C. Christodoulou; George Minadakis; Christiana Demetriou; Eleni Zamba-Papanicolaou; George M. Spyrou (BIBE, 2019)

The Effect of a Spastic Ataxia Associated GBA2 Mutation on Protein-Protein Interactions and Pathways. - Andrea C. Kakouri; Christina Votsi; Marios Tomazou; Kyproula Christodoulou; George M. Spyrou (BIBE, 2019)

Exploring Fibrotic Disease Networks to Identify Common Molecular Mechanisms with IPF. - Evangelos Karatzas; Alex Delis; George Kolios; George M. Spyrou (BIBE, 2019)

Design and Initial Implementation of a Computer Aided Diagnosis System for PET/CT Solitary Pulmonary Nodule Risk Estimation. - George M. Tzanoukos; Pavlos Kafouris; Alexandros Georgakopoulos; Anastasios Gaitanis; Dimitris Maroulis; Sofia Chatziioannou; George M. Spyrou (BIBE, 2019)

In Silico Assessment of the Structural, Functional and Stability Impact of a Nonsense PRF1 Mutation with Uncertain Clinical Significance; Identified in 2 Unrelated Cypriot Triple-Negative Breast Cancer Patients. - Maria Zanti; Maria Loizidou; Margarita Zachariou; Kyriaki Michailidou; Kyriacos C. Kyriacou; Andreas Hadjisavvas; George M. Spyrou (BIBE, 2019)

Computational profiling of the gut-brain axis: microflora dysbiosis insights to neurological disorders. - Nikolas Dovrolis; George Kolios; George M. Spyrou; Ioanna Maroulakou (Briefings Bioinform., 2019)

Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches. - Anastasis Oulas; George Minadakis; Margarita Zachariou; Kleitos Sokratous; Marilena M. Bourdakou; George M. Spyrou (Briefings Bioinform., 2019)

PathwayConnector: finding complementary pathways to enhance functional analysis. - George Minadakis; Margarita Zachariou; Anastasis Oulas; George M. Spyrou (Bioinform., 2019)

Content driven clustering algorithm combining density and distance functions. - Emmanouil K. Ikonomakis; George M. Spyrou; Michael N. Vrahatis (Pattern Recognit., 2019)

Revealing Clusters of Connected Pathways Through Multisource Data Integration in Huntington's Disease and Spastic Ataxia. - Andrea C. Kakouri; Christiana C. Christodoulou; Margarita Zachariou; Anastasis Oulas; George Minadakis; Christiana A. Demetriou; Christina Votsi; Eleni Zamba-Papanicolaou; Kyproula Christodoulou; George M. Spyrou (IEEE J. Biomed. Health Informatics, 2019)

ChemBioServer 2.0: an advanced web server for filtering, clustering and networking of chemical compounds facilitating both drug discovery and repurposing. - Evangelos Karatzas; Juan Eiros Zamora; Emmanouil Athanasiadis; Dimitris Dellis; Zoe Cournia; George M. Spyrou (Bioinform., 2020)

PathWalks: identifying pathway communities using a disease-related map of integrated information. - Evangelos Karatzas; Margarita Zachariou; Marilena M. Bourdakou; George Minadakis; Anastasis Oulas; George Kolios; Alex Delis; George M. Spyrou (Bioinform., 2020)

Computational insights on the molecular mechanisms across breast cancer progression combining gene differential expression and co-expression. - Emmanouil K. Ikonomakis; Marilena M. Bourdakou; George Kolios; Michael N. Vrahatis; George M. Spyrou (BHI, 2021)

Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches. - Anna Onisiforou; George M. Spyrou (Briefings Bioinform., 2021)

Multi-omics data integration and network-based analysis drives a multiplex drug repurposing approach to a shortlist of candidate drugs against COVID-19. - Marios Tomazou; Marilena M. Bourdakou; George Minadakis; Margarita Zachariou; Anastasis Oulas; Evangelos Karatzas; Eleni M. Loizidou; Andrea C. Kakouri; Christiana C. Christodoulou; Kyriaki Savva; Maria Zanti; Anna Onisiforou; et al. (Briefings Bioinform., 2021)

Performance evaluation of pipelines for mapping, variant calling and interval padding, for the analysis of NGS germline panels. - Maria Zanti; Kyriaki Michailidou; Maria Loizidou; Christina Machattou; Panagiota Pirpa; Kyproula Christodoulou; George M. Spyrou; Kyriacos Kyriacou; Andreas Hadjisavvas (BMC Bioinform., 2021)

Vir2Drug: a drug repurposing framework based on protein similarities between pathogens. - George Minadakis; Marios Tomazou; Nikolas Dietis; George M. Spyrou (Briefings Bioinform., 2023)

Combining clinical and molecular data for personalized treatment in acute myeloid leukemia: A machine learning approach. - Nestoras Karathanasis; Panayiota L. Papasavva; Anastasis Oulas; George M. Spyrou (Comput. Methods Programs Biomed., 2024)

Ranking of cell clusters in a single-cell RNA-sequencing analysis framework using prior knowledge. - Anastasis Oulas; Kyriaki Savva; Nestoras Karathanasis; George M. Spyrou (PLoS Comput. Biol., 2024)

Topological influence of immediate-early genes in brain genetic networks and their link to Alzheimer's disease. - Margarita Zachariou; Eleni M. Loizidou; George M. Spyrou (Comput. Biol. Medicine, 2025)