A penalized spline fitting method to optimize geometric parameters of arterial centerlines extracted from medical images. - Masaharu Kobayashi; Katsuyuki Hoshina; Youkou Nemoto; Shu Takagi; Masaaki Shojima; Motoharu Hayakawa; Shigeki Yamada; Marie Oshima (Comput. Medical Imaging Graph., 2020)