Single-nucleus and machine-learning integration identifies HLA-DRA and FTL as immune-metabolic axes and traditional Chinese medicine-targetable hubs in calcific aortic valve disease. - Qiang Zhao; Kun Wang; Dongbin Xiao; Huandong Wang; Peiyao Ma; Ruishan Liu; Shenke Kong (J. Comput. Aided Mol. Des., 2026)