caBIG™ Compatibility Review System: Software to Support the Evaluation of Applications Using Defined Interoperability Criteria. - Robert R. Freimuth; Michael W. Schauer; Preeti Lodha; Poornima Govindrao; Rakesh Nagarajan; Christopher G. Chute (AMIA, 2008)

Mining Genotype-Phenotype Associations from Electronic Health Records and Biorepositories using Semantic Web Technologies. - Jyotishman Pathak; Richard C. Kiefer; Robert R. Freimuth; Suzette J. Bielinski; Christopher G. Chute (AMIA, 2012)

A Semantic-Web Oriented Representation of Clinical Element Model for Secondary Use of Electronic Healthcare Data. - Cui Tao; Guoqian Jiang; Thomas A. Oniki; Robert R. Freimuth; Jyotishman Pathak; Qian Zhu 003; Deepak K. Sharma; Stanley M. Huff; Christopher G. Chute (HISB, 2012)

Integrating VA's NDF-RT Drug Terminology with PharmGKB: Preliminary Results. - Jyotishman Pathak; Laura C. Weiss; Matthew J. Durski; Qian Zhu 003; Robert R. Freimuth; Christopher G. Chute (Pacific Symposium on Biocomputing, 2012)

SNP interaction detection with Random Forests in high-dimensional genetic data. - Stacey J. Winham; Colin L. Colby; Robert R. Freimuth; Xin Wang; Mariza de Andrade; Marianne Huebner; Joanna M. Biernacka (BMC Bioinform., 2012)

Life sciences domain analysis model. - Robert R. Freimuth; Elaine T. Freund; Lisa Schick; Mukesh K. Sharma; Grace A. Stafford; Baris E. Suzek; Joyce Hernandez; Jason Hipp; Jenny M. Kelley; Konrad Rokicki; Sue Pan; Andrew J. Buckler; et al. (J. Am. Medical Informatics Assoc., 2012)

Using standardized clinical data modeling and knowledge representation to compute pharmacogenomic data elements. - Qian Zhu 003; Jyotishman Pathak; Robert R. Freimuth; Christopher G. Chute (AMIA, 2013)

An RDF/OWL Knowledge Base for Query Answering and Decision Support in Clinical Pharmacogenetics. - Matthias Samwald; Robert R. Freimuth; Joanne S. Luciano; Simon M. Lin; Robert L. Powers; M. Scott Marshall; Klaus-Peter Adlassnig; Michel Dumontier; Richard D. Boyce (MedInfo, 2013)

A semantic-web oriented representation of the clinical element model for secondary use of electronic health records data. - Cui Tao; Guoqian Jiang; Thomas A. Oniki; Robert R. Freimuth; Qian Zhu 003; Deepak K. Sharma; Jyotishman Pathak; Stanley M. Huff; Christopher G. Chute (J. Am. Medical Informatics Assoc., 2013)

Harmonization and semantic annotation of data dictionaries from the Pharmacogenomics Research Network: A case study. - Qian Zhu 003; Robert R. Freimuth; Zonghui Lian; Scott Bauer; Jyotishman Pathak; Cui Tao; Matthew J. Durski; Christopher G. Chute (J. Biomed. Informatics, 2013)

Disambiguation of PharmGKB drug-disease relations with NDF-RT and SPL. - Qian Zhu 003; Robert R. Freimuth; Jyotishman Pathak; Matthew J. Durski; Christopher G. Chute (J. Biomed. Informatics, 2013)

A weighted random forests approach to improve predictive performance. - Stacey J. Winham; Robert R. Freimuth; Joanna M. Biernacka (Stat. Anal. Data Min., 2013)

Evaluation of RxNorm for Medication Clinical Decision Support. - Robert R. Freimuth; Kelly Wix; Qian Zhu 003; Mark Siska; Christopher G. Chute (AMIA, 2014)

A Template for Authoring and Adapting Genomic Medicine Content in the eMERGE Infobutton Project. - Casey L. Overby; Luke V. Rasmussen; Andrea L. Hartzler; John J. Connolly; Josh F. Peterson; RoseMary Hedberg; Robert R. Freimuth; Brian H. Shirts; Joshua C. Denny; Eric B. Larson; Christopher G. Chute; Gail P. Jarvik; et al. (AMIA, 2014)

Creating Shareable Clinical Decision Support Rules for a Pharmacogenomics Clinical Guideline Using Structured Knowledge Representation. - Margaret K. Linan; Davide Sottara; Robert R. Freimuth (AMIA, 2015)

Public Implementation Resources for Genomic Medicine. - Josh F. Peterson; Marc S. Williams; Casey L. Overby; Robert R. Freimuth; Iftikhar J. Kullo (AMIA, 2015)

CSER and eMERGE: current and potential state of the display of genetic information in the electronic health record. - Brian H. Shirts; Joseph S. Salama; Samuel J. Aronson; Wendy K. Chung; Stacy W. Gray; Lucia A. Hindorff; Gail P. Jarvik; Sharon E. Plon; Elena M. Stoffel; Peter Tarczy-Hornoch; Eliezer M. Van Allen; Karen E. Weck; et al. (J. Am. Medical Informatics Assoc., 2015)

Pharmacogenomic knowledge representation, reasoning and genome-based clinical decision support based on OWL 2 DL ontologies. - Matthias Samwald; José Antonio Miñarro-Giménez; Richard D. Boyce; Robert R. Freimuth; Klaus-Peter Adlassnig; Michel Dumontier (BMC Medical Informatics Decis. Mak., 2015)

Knowledge as a Service at the Point of Care. - Jane L. Shellum; Robert R. Freimuth; Steve G. Peters; Rick Nishimura; Rajeev Chaudhry; Steve Demuth; Amy Knopp; Tim Miksch; Dawn S. Milliner (AMIA, 2016)

The Clinical Pharmacogenetics Implementation Consortium (CPIC) Term Standardization for Clinical Pharmacogenetic Test Results: Alleles and Phenotypes. - James M. Hoffman; Henry M. Dunnenberger; Jonathan D. Burlison; Michelle Whirl Carrillo; Robert R. Freimuth; Marc S. Williams; Stuart A. Scott; Josh F. Peterson; Heidi L. Rehm; Teri E. Klein; Mary V. Relling; Kelly E. Caudle (CRI, 2016)

Towards a Standard Ontology Metadata Model. - Hua Min; Stuart Turner; Sherri de Coronado; Brian Davis; Trish Whetzel; Robert R. Freimuth; Harold R. Solbrig; Richard C. Kiefer; Michael Riben; Grace A. Stafford; Lawrence W. Wright; Riki Ohira (ICBO/BioCreative, 2016)

Translational Bioinformatics 101. - Jessica D. Tenenbaum; Subha Madhavan; Robert R. Freimuth; Joshua C. Denny; Lewis J. Frey (PSB, 2016)

Practical considerations for implementing genomic information resources. - Casey L. Overby; John J. Connolly; Christopher G. Chute; Joshua C. Denny; Robert R. Freimuth; Andrea L. Hartzler; Ingrid A. Holm; Shannon F. Manzi; Jyotishman Pathak; Peggy L. Peissig; Maureen E. Smith; Marc S. Williams; et al. (Appl. Clin. Inform., 2016)

Integrating Genomic Resources with Electronic Health Records using the HL7 Infobutton Standard. - Casey L. Overby; Guilherme Del Fiol; Wendy S. Rubinstein; Donna R. Maglott; Tristan Nelson; Aleksandar Milosavljevic; Christa Martin; Scott Goehringer; Robert R. Freimuth; Marc S. Williams; Bret S. E. Heale (Appl. Clin. Inform., 2016)

Developing knowledge resources to support precision medicine: principles from the Clinical Pharmacogenetics Implementation Consortium (CPIC). - James M. Hoffman; Henry M. Dunnenberger; J. Kevin Hicks; Kelly E. Caudle; Michelle Whirl Carrillo; Robert R. Freimuth; Marc S. Williams; Teri E. Klein; Josh F. Peterson (J. Am. Medical Informatics Assoc., 2016)

An informatics research agenda to support precision medicine: seven key areas. - Jessica D. Tenenbaum; Paul Avillach; Marge M. Benham-Hutchins; Matthew K. Breitenstein; Erin L. Crowgey; Mark A. Hoffman; Xia Jiang; Subha Madhavan; John E. Mattison; Radhakrishnan Nagarajan; Bisakha Ray; Dmitriy Shin; et al. (J. Am. Medical Informatics Assoc., 2016)

Harnessing next-generation informatics for personalizing medicine: a report from AMIA's 2014 Health Policy Invitational Meeting. - Laura K. Wiley; Peter Tarczy-Hornoch; Joshua C. Denny; Robert R. Freimuth; Casey L. Overby; Nigam Shah; Ross D. Martin; Indra Neil Sarkar (J. Am. Medical Informatics Assoc., 2016)

The genomic CDS sandbox: An assessment among domain experts. - Ayesha Aziz; Kensaku Kawamoto; Karen Eilbeck; Marc S. Williams; Robert R. Freimuth; Mark A. Hoffman; Luke V. Rasmussen; Casey Lynnette Overby; Brian H. Shirts; James M. Hoffman; Brandon M. Welch (J. Biomed. Informatics, 2016)

Development & Implementation of a Clinical Decision Support Tool for Familial Hypercholesterolemia. - Ali Hasnie; Pedro J. Caraballo; Robert R. Freimuth; Iftikhar J. Kullo (AMIA, 2017)

A Scalable Encoding Scheme for Clinical Genomic Results Delivered Through Web Services and a Mobile Application. - Shashwat Nagar; Richard C. Kiefer; Robert R. Freimuth (AMIA, 2018)

Empowering genomic medicine by establishing critical sequencing result data flows: the eMERGE example. - Samuel J. Aronson; Lawrence J. Babb; Darren C. Ames; Richard A. Gibbs; Eric Venner; John J. Connelly; Keith Marsolo; Chunhua Weng; Marc S. Williams; Andrea L. Hartzler; Wayne H. Liang; James D. Ralston; et al. (J. Am. Medical Informatics Assoc., 2018)

Sync for Genes: Integrating Genetic Information at the Point of Care. - Stephanie Garcia; Robert R. Freimuth; David E. Jones; Robert P. Milius (AMIA, 2019)

Automated Extraction of Computable Clinical Decision Support Rules from an Electronic Health Record (EHR) System. - Branden C. Hickey; Adam M. Bartscher; Marc Sainvil; Robert R. Freimuth; Jane L. Shellum; Davide Sottara (AMIA, 2019)

Sync for Genes: Making Clinical Genomics Available for Precision Medicine at the Point-of-Care. - Stephanie J. Garcia; Teresa Zayas-Cabán; Robert R. Freimuth (Appl. Clin. Inform., 2020)

Content in Context - Individualizing Knowledge Resources for Delivery at the Point of Care. - Jane L. Shellum; Davide Sottara; Robert R. Freimuth; Aaron Nathan; Adam M. Bartscher (AMIA, 2021)

The GA4GH Variation Representation Specification (VRS): a Computational Framework for the Precise Representation of Molecular Variation. - Alex H. Wagner; Lawrence J. Babb; Melissa S. Cline; Helen Schuilenburg; Tristan Nelson; Robert R. Freimuth; Reece Hart (AMIA, 2021)

Modeling Variant Annotation (VA) Therapeutic Association Statements using a SEPIO-Based Workflow. - Yiqing Zhao; Matthew Brush; Hongfang Liu; Robert R. Freimuth (AMIA, 2021)

Infobuttons for Genomic Medicine: Requirements and Barriers. - Luke V. Rasmussen; John J. Connolly; Guilherme Del Fiol; Robert R. Freimuth; Douglas B. Pet; Josh F. Peterson; Brian H. Shirts; Justin B. Starren; Marc S. Williams; Nephi Walton; Casey Overby Taylor (Appl. Clin. Inform., 2021)

Recommendations for the safe, effective use of adaptive CDS in the US healthcare system: an AMIA position paper. - Carolyn Petersen; Jeffery Smith; Robert R. Freimuth; Kenneth W. Goodman; Gretchen Purcell Jackson; Joseph L. Kannry; Hongfang Liu; Subha Madhavan; Dean F. Sittig; Adam Wright (J. Am. Medical Informatics Assoc., 2021)

Genomic considerations for FHIR®; eMERGE implementation lessons. - Mullai Murugan; Lawrence J. Babb; Casey Overby Taylor; Luke V. Rasmussen; Robert R. Freimuth; Eric Venner; Fei Yan; Victoria Yi; Stephen J. Granite; Hana Zouk; Samuel J. Aronson; Kevin Power; et al. (J. Biomed. Informatics, 2021)

A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources. - Ken Wiley; Laura Findley; Madison Goldrich; Tejinder K. Rakhra-Burris; Ana Stevens; Pamela Williams; Carol J. Bult; Rex L. Chisholm; Patricia Deverka; Geoffrey S. Ginsburg; Eric D. Green; Gail P. Jarvik; et al. (J. Am. Medical Informatics Assoc., 2022)

Under-specification as the source of ambiguity and vagueness in narrative phenotype algorithm definitions. - Jingzhi Yu; Jennifer A. Pacheco; Anika S. Ghosh; Yuan Luo 001; Chunhua Weng; Ning Shang; Barbara Benoit; David S. Carrell; Robert J. Carroll; Ozan Dikilitas; Robert R. Freimuth; Vivian S. Gainer; et al. (BMC Medical Informatics Decis. Mak., 2022)

Leveraging a pharmacogenomics knowledgebase to formulate a drug response phenotype terminology for genomic medicine. - Yiqing Zhao; Matthew Brush; Chen Wang 001; Alex H. Wagner; Hongfang Liu; Robert R. Freimuth (Bioinform., 2022)

Representing NIH Genetic Test Registry Data in the FHIR Genomic Study Resource. - Aly Khalifa; Robert R. Freimuth (ICIMTH, 2023)

Enabling the clinical application of artificial intelligence in genomics: a perspective of the AMIA Genomics and Translational Bioinformatics Workgroup. - Nephi A. Walton; Radhakrishnan Nagarajan; Chen Wang 001; Murat Sincan; Robert R. Freimuth; David B. Everman; Derek C. Walton; Scott P. McGrath; Dominick J. Lemas; Panayiotis V. Benos; Alexander V. Alekseyenko; Qianqian Song; et al. (J. Am. Medical Informatics Assoc., 2024)