A tiered approach is more cost effective than traditional pharmacist-based review for classifying computer-detected signals as adverse drug events. - Carol Hope; J. Marc Overhage; Andrew C. Seger; Evgenia Y. Teal; Vera Mills; Julie M. Fiskio; Tejal K. Gandhi; David W. Bates; Michael D. Murray (J. Biomed. Informatics, 2003)