Xiaobo Zhou

Affiliations:
  • Wake Forest School of Medicine, Department of Radiology, Winston-Salem, USA
  • Houston Methodist Hospital, Weill Cornell Medical College, TX, USA (former)
  • Harvard Medical School, Boston, MA, USA (former)
  • Brigham and Women's Hospital, Radiology Department, Boston, MA (former)
  • Texas A&M University, Department of Electrical Engineering, College Station, TX, USA (2001 - 2003)
  • University of Missouri-Columbia, Department of Computer Science, MO, USA (2000)
  • Huawei Technologies Co., Ltd., Beijing, China (1999 - 2000)
  • Tsinghua University, Department of Automation, Beijing, China (1998 - 1999)
  • Peking University, Department of Mathematics, Beijing, China (PhD 1998)


According to our database1, Xiaobo Zhou authored at least 137 papers between 2003 and 2021.

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Bibliography

2021
Revealing dynamic regulations and the related key proteins of myeloma-initiating cells by integrating experimental data into a systems biological model.
Bioinform., 2021

2020
Transparency-guided ensemble convolutional neural network for the stratification between pseudoprogression and true progression of glioblastoma multiform in MRI.
J. Vis. Commun. Image Represent., 2020

2019
DC-Al GAN: Pseudoprogression and True Tumor Progression of Glioblastoma multiform Image Classification Based On DCGAN and Alexnet.
CoRR, 2019

Semantic Prior Guided Face Inpainting.
Proceedings of the MMAsia '19: ACM Multimedia Asia, Beijing, China, December 16-18, 2019, 2019

2017
Reconstruction-Based Digital Dental Occlusion of the Partially Edentulous Dentition.
IEEE J. Biomed. Health Informatics, 2017

Annotating function to differentially expressed LincRNAs in myelodysplastic syndrome using a network-based method.
Bioinform., 2017

String-Based Models for Predicting RNA-Protein Interaction.
Proceedings of the 8th ACM International Conference on Bioinformatics, 2017

2016
Pseudo progression identification of glioblastoma with dictionary learning.
Comput. Biol. Medicine, 2016

Prediction of soft tissue deformations after CMF surgery with incremental kernel ridge regression.
Comput. Biol. Medicine, 2016

Two-Stage Simulation Method to Improve Facial Soft Tissue Prediction Accuracy for Orthognathic Surgery.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention - MICCAI 2016, 2016

A Novel Computer-Aided Surgical Simulation (CASS) System to Streamline Orthognathic Surgical Planning.
Proceedings of the Medical Imaging and Augmented Reality - 7th International Conference, 2016

FEM Simulation with Realistic Sliding Effect to Improve Facial-Soft-Tissue-Change Prediction Accuracy for Orthognathic Surgery.
Proceedings of the Medical Imaging and Augmented Reality - 7th International Conference, 2016

2015
Novel 3D GPU based numerical parallel diffusion algorithms in cylindrical coordinates for health care simulation.
Math. Comput. Simul., 2015

Automated Three-Piece Digital Dental Articulation.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention - MICCAI 2015, 2015

Prediction of facial soft tissue deformations with improved rubin-bodner model after craniomaxillofacial (CMF) surgery.
Proceedings of the 2015 IEEE International Conference on Image Processing, 2015

2014
Modeling Cell-Cell Interactions in Regulating Multiple Myeloma Initiating Cell Fate.
IEEE J. Biomed. Health Informatics, 2014

Multiscale agent-based modelling of ovarian cancer progression under the stimulation of the STAT 3 pathway.
Int. J. Data Min. Bioinform., 2014

Characterization of p38 MAPK isoforms for drug resistance study using systems biology approach.
Bioinform., 2014

2013
Systems Modeling of Anti-apoptotic Pathways in Prostate Cancer: Psychological Stress Triggers a Synergism Pattern Switch in Drug Combination Therapy.
PLoS Comput. Biol., 2013

A novel network and sparsity constraint regression model for functional module identification in genomic data analysis.
Int. J. Data Min. Bioinform., 2013

FusionQ: a novel approach for gene fusion detection and quantification from paired-end RNA-Seq.
BMC Bioinform., 2013

2012
A Computational model for compressed sensing RNAi cellular screening.
BMC Bioinform., 2012

Multi-scale agent-based brain cancer modeling and prediction of TKI treatment response: Incorporating EGFR signaling pathway and angiogenesis.
BMC Bioinform., 2012

A novel missense-mutation-related feature extraction scheme for 'driver' mutation identification.
Bioinform., 2012

Incremental Kernel Ridge Regression for the Prediction of Soft Tissue Deformations.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention - MICCAI 2012, 2012

A Novel Approach Based on Joint Optimization of Alignment and Statistical Surface Representation with Wavelet Transform for CBCT Segmentation.
Proceedings of the Computational Intelligence Methods for Bioinformatics and Biostatistics, 2012

2011
A Global Spatial Similarity Optimization Scheme to Track Large Numbers of Dendritic Spines in Time-Lapse Confocal Microscopy.
IEEE Trans. Medical Imaging, 2011

Peak Tree: A New Tool for Multiscale Hierarchical Representation and Peak Detection of Mass Spectrometry Data.
IEEE ACM Trans. Comput. Biol. Bioinform., 2011

NSMAP: A Method for Spliced Isoforms Identification and Quantification from RNA-Seq.
BMC Bioinform., 2011

An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data.
Bioinform., 2011

Searchlight CT: a new reconstruction method for collimated X-ray tomography.
Proceedings of the 5th International ICST Conference on Performance Evaluation Methodologies and Tools Communications, 2011

A double thresholding method for cancer stem cell detection.
Proceedings of the 7th International Symposium on Image and Signal Processing and Analysis, 2011

Symmetry-based presentation for stem-cell image segmentation.
Proceedings of the IEEE 1st International Conference on Computational Advances in Bio and Medical Sciences, 2011

2010
Bayesian peptide peak detection for high resolution TOF mass spectrometry.
IEEE Trans. Signal Process., 2010

Multiple Nuclei Tracking Using Integer Programming for Quantitative Cancer Cell Cycle Analysis.
IEEE Trans. Medical Imaging, 2010

An Automatic and Robust Algorithm of Reestablishment of Digital Dental Occlusion.
IEEE Trans. Medical Imaging, 2010

Oriented Markov Random Field Based Dendritic Spine Segmentation for Fluorescence Microscopy Images.
Neuroinformatics, 2010

Semi-supervised drug-protein interaction prediction from heterogeneous biological spaces.
BMC Syst. Biol., 2010

An information-flow-based model with dissipation, saturation and direction for active pathway inference.
BMC Syst. Biol., 2010

A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties of functional gene network.
BMC Bioinform., 2010

Conditional random pattern model for copy number aberration detection.
BMC Bioinform., 2010

Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines.
BMC Bioinform., 2010

Reconstruction of the neuromuscular junction connectome.
Bioinform., 2010

Correlation-based cluster-space transform for major adverse cardiac event prediction.
Proceedings of the IEEE International Conference on Systems, 2010

Automated Digital Dental Articulation.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention, 2010

Optimal Live Cell Tracking for Cell Cycle Study Using Time-Lapse Fluorescent Microscopy Images.
Proceedings of the Machine Learning in Medical Imaging, First International Workshop, 2010

Ratio-hypothesis-based Fuzzy Fusion with Application to Classification of Cellular Morphologies.
Proceedings of the BIOSIGNALS 2010, 2010

A graph-based elastic net for variable selection and module identification for genomic data analysis.
Proceedings of the 2010 IEEE International Conference on Bioinformatics and Biomedicine, 2010

2009
A Novel Cell Segmentation Method and Cell Phase Identification Using Markov Model.
IEEE Trans. Inf. Technol. Biomed., 2009

Unraveling the signal-transduction networks in cancer metastasis [Life Sciences].
IEEE Signal Process. Mag., 2009

Recognition and analysis of cell nuclear phases for high-content screening based on morphological features.
Pattern Recognit., 2009

Online phenotype discovery based on minimum classification error model.
Pattern Recognit., 2009

Growing enzyme gene networks by integration of gene expression, motif sequence, and metabolic information.
Pattern Recognit., 2009

Automated Axon Tracking of 3D Confocal Laser Scanning Microscopy Images Using Guided Probabilistic Region Merging.
Neuroinformatics, 2009

An Automated Pipeline for Dendrite Spine Detection and Tracking of 3D Optical Microscopy Neuron Images of In Vivo Mouse Models.
Neuroinformatics, 2009

An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling.
J. Biomed. Informatics, 2009

Imaging informatics for personalised medicine: applications and challenges.
Int. J. Funct. Informatics Pers. Medicine, 2009

3D neuron dendritic spine detection and dendrite reconstruction.
Int. J. Comput. Aided Eng. Technol., 2009

Analysis and recognition of touching cell images based on morphological structures.
Comput. Biol. Medicine, 2009

Conditional random pattern algorithm for LOH inference and segmentation.
Bioinform., 2009

Cell Segmentation Using Front Vector Flow Guided Active Contours.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention, 2009

An Interactive Geometric Technique for Upper and Lower Teeth Segmentation.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention, 2009

Online Three-Dimensional Dendritic Spines Mophological Classification Based on Semi-Supervised Learning.
Proceedings of the 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Boston, MA, USA, June 28, 2009

Integrating Multi-Scale Blob/Curvilinear Detector Techniques and Multi-Level Sets for Automated Segmentation of Stem Cell Images.
Proceedings of the 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Boston, MA, USA, June 28, 2009

A Novel Surface-Based Geometric Approach for 3D Dendritic Spine Detection from Multi-Photon Excitation Microscopy Images.
Proceedings of the 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Boston, MA, USA, June 28, 2009

Equilibrium modeling for 3D curvilinear structure tracking of confocal microscopy images.
Proceedings of the International Conference on Image Processing, 2009

2008
Automatic Segmentation of High-Throughput RNAi Fluorescent Cellular Images.
IEEE Trans. Inf. Technol. Biomed., 2008

Registration of 3-D CT and 2-D Flat Images of Mouse via Affine Transformation.
IEEE Trans. Inf. Technol. Biomed., 2008

Computational Prediction Models for Early Detection of Risk of Cardiovascular Events Using Mass Spectrometry Data.
IEEE Trans. Inf. Technol. Biomed., 2008

Computational Systems Bioinformatics and Bioimaging for Pathway Analysis and Drug Screening.
Proc. IEEE, 2008

An Automated Method for Cell Detection in Zebrafish.
Neuroinformatics, 2008

Workflow and Methods of High-Content Time-Lapse Analysis for Quantifying Intracellular Calcium Signals.
Neuroinformatics, 2008

3D Axon Structure Extraction and Analysis in Confocal Fluorescence Microscopy Images.
Neural Comput., 2008

Comparison of reversible-jump Markov-chain-Monte-Carlo learning approach with other methods for missing enzyme identification.
J. Biomed. Informatics, 2008

Peak detection using peak tree approach for mass spectrometry data.
Int. J. Hybrid Intell. Syst., 2008

Comparison of Bayesian and regression models in missing enzyme identification.
Int. J. Bioinform. Res. Appl., 2008

Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens.
BMC Bioinform., 2008

Novel cell segmentation and online SVM for cell cycle phase identification in automated microscopy.
Bioinform., 2008

3D Dendrite Reconstruction and Spine Identification.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention, 2008

Classification of Mass Spectrometry Based Protein Markers by Kriging Error Matching.
Proceedings of the Advances in Mass Data Analysis of Images and Signals in Medicine, 2008

Detection and Analysis of Cell Nuclear Phases.
Proceedings of the Knowledge-Based Intelligent Information and Engineering Systems, 2008

Reversible jump MCMC approach for peak identification for stroke SELDI mass spectrometry using mixture model.
Proceedings of the Proceedings 16th International Conference on Intelligent Systems for Molecular Biology (ISMB), 2008

Classification of Proteomic Signals by Block Kriging Error Matching.
Proceedings of the Image and Signal Processing - 3rd International Conference, 2008

Bayesian peak detection for Pro-TOF MS MALDI data.
Proceedings of the IEEE International Conference on Acoustics, 2008

Active microscopic cellular image annotation by superposable graph transduction with imbalanced labels.
Proceedings of the 2008 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR 2008), 2008

2007
Automated Axon Tracking of 3D Confocal Laser Scanning Microscopy Images Using Guided Probabilistic Region Merging.
Neuroinformatics, 2007

Automated neurite extraction using dynamic programming for high-throughput screening of neuron-based assays.
NeuroImage, 2007

Dendritic spine detection using curvilinear structure detector and LDA classifier.
NeuroImage, 2007

Automated recognition of cellular phenotypes by support vector machines with feature reduction.
Int. J. Knowl. Based Intell. Eng. Syst., 2007

Fuzzy information fusion of classification models for high-throughput image screening of cancer cells in time-lapse microscopy.
Int. J. Knowl. Based Intell. Eng. Syst., 2007

Context based mixture model for cell phase identification in automated fluorescence microscopy.
BMC Bioinform., 2007

A Novel Coarse-to-Fine Adaptation Segmentation Approach for Cellular Image Analysis.
Proceedings of the Advances in Multimedia Modeling, 2007

Automated Segmentation of Drosophila RNAi Fluorescence Cellular Images Using Graph Cuts.
Proceedings of the Advances in Multimedia Modeling, 2007

A Novel Image Feature for Nuclear-Phase Classification in High Content Screening.
Proceedings of the Advances in Mass Data Analysis of Signals and Images in Medicine, 2007

Registration of 3D FMT and CT Images of Mouse Via Affine Transformation with Bayesian Iterative Closest Points.
Proceedings of the Advances in Neural Networks, 2007

Detecting Biomarkers for Major Adverse Cardiac Events Using SVM with PLS Feature Selection and Extraction.
Proceedings of the Advances in Neural Networks, 2007

Study of CuO Nanoparticle-induced Cell Death by High Content Cellular Fluorescence Imaging and Analysis.
Proceedings of the International Symposium on Circuits and Systems (ISCAS 2007), 2007

Automated Spine Detection Using Curvilinear Structure Detector and LDA Classifier.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

Dynamic Local Tracing for 3d Axon Curvilinear Structure Detection from Microscopic Image Stack.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

Novel Cell Segmentation and Online Learning Algorithms for Cell Phase Identification in Automated Time-lapse Microscopy.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

3-D Centerline Extraction of Axons in Microscopic Stacks for the Study of Motor Neuron Behavior in Developing Muscles.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

Graph Cut Based Active Contour for Automated Cellular Image Segmentation in High Throughput Rna Interface (rnai) Screening.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

Tracking of Migrating Glioma Cells in Feature Space.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

A 3D Self-Adjust Region Growing Method for Axon Extraction.
Proceedings of the International Conference on Image Processing, 2007

Graph Theory Application in Cell Nuleus Segmentation, Tracking and Identification.
Proceedings of the 7th IEEE International Conference on Bioinformatics and Bioengineering, 2007

A Simulation-Based 3D Axon Axis Extraction in Confocal Fluorescence Microscopy Images.
Proceedings of the 7th IEEE International Conference on Bioinformatics and Bioengineering, 2007

2006
Nuclei Segmentation Using Marker-Controlled Watershed, Tracking Using Mean-Shift, and Kalman Filter in Time-Lapse Microscopy.
IEEE Trans. Circuits Syst. I Regul. Pap., 2006

Automated Segmentation of Drosophila RNAi Fluorescence Cellular Images Using Deformable Models.
IEEE Trans. Circuits Syst. I Regul. Pap., 2006

Automated segmentation, classification, and tracking of cancer cell nuclei in time-lapse microscopy.
IEEE Trans. Biomed. Eng., 2006

Informatics challenges of high-throughput microscopy.
IEEE Signal Process. Mag., 2006

Mutual information-based feature selection in studying perturbation of dendritic structure caused by TSC2 inactivation.
Neuroinformatics, 2006

Bayesian variable selection for gene expression modeling with regulatory motif binding sites in neuroinflammatory events.
Neuroinformatics, 2006

A computerized cellular imaging system for high content analysis in Monastrol suppressor screens.
J. Biomed. Informatics, 2006

Integrated Algorithms for Image Analysis and Classification of Nuclear Division for High-Content Cell-Cycle Screening.
Int. J. Comput. Intell. Appl., 2006

Protein structure similarity from principle component correlation analysis.
BMC Bioinform., 2006

Gene Selection Using Gaussian Kernel Support Vector Machine Based Recursive Feature Elimination with Adaptive Kernel Width Strategy.
Proceedings of the Rough Sets and Knowledge Technology, First International Conference, 2006

Automated Recognition of Cellular Phenotypes by Support Vector Machines with Feature Reduction.
Proceedings of the Knowledge-Based Intelligent Information and Engineering Systems, 2006

Identification of Cell-Cycle Phases Using Neural Network and Steerable Filter Features.
Proceedings of the Advances in Neural Networks - ISNN 2006, Third International Symposium on Neural Networks, Chengdu, China, May 28, 2006

Automated labeling of neurites in fluorescence microscopy images.
Proceedings of the 2006 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2006

An Effective System for Optical Microscopy Cell Image Segmentation, Tracking and Cell Phase Identification.
Proceedings of the International Conference on Image Processing, 2006

Segmentation of Drosophila RNAI Fluorescence Images Using Level Sets.
Proceedings of the International Conference on Image Processing, 2006

Robust Feature Extraction and Reduction of Mass Spectrometry Data for Cancer Classification.
Proceedings of the Workshops Proceedings of the 6th IEEE International Conference on Data Mining (ICDM 2006), 2006

2005
Towards Automated Cellular Image Segmentation for RNAi Genome-Wide Screening.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention, 2005

Model the Relationship Between Gene Expression and TFBSs Using a Simplified Neural Network with Bayesian Variable Selection.
Proceedings of the Advances in Neural Networks - ISNN 2005, Second International Symposium on Neural Networks, Chongqing, China, May 30, 2005

Dynamic sub-cellular behavior study in high content imaging using a multi-threshold approach.
Proceedings of the International Symposium on Circuits and Systems (ISCAS 2005), 2005

A computer-based system to analyze neuron images.
Proceedings of the International Symposium on Circuits and Systems (ISCAS 2005), 2005

2004
Performance comparisons of channel estimation techniques in multipath fading CDMA.
IEEE Trans. Wirel. Commun., 2004

A Bayesian approach to nonlinear probit gene selection and classification.
J. Frankl. Inst., 2004

Gene Clustering Based on Clusterwide Mutual Information.
J. Comput. Biol., 2004

Cancer classification and prediction using logistic regression with Bayesian gene selection.
J. Biomed. Informatics, 2004

Gene Prediction Using Multinomial Probit Regression with Bayesian Gene Selection.
EURASIP J. Adv. Signal Process., 2004

FIR-median hybrid filters with polynomial fitting.
Digit. Signal Process., 2004

A Bayesian connectivity-based approach to constructing probabilistic gene regulatory networks.
Bioinform., 2004

2003
Channel estimation for OFDM systems using adaptive radial basis function networks.
IEEE Trans. Veh. Technol., 2003

Construction of genomic networks using mutual-information clustering and reversible-jump Markov-chain-Monte-Carlo predictor design.
Signal Process., 2003

Receiver techniques for ultra-wide-band multiuser systems over fading multipath channels.
J. Commun. Networks, 2003

Missing-value estimation using linear and non-linear regression with Bayesian gene selection.
Bioinform., 2003


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