Eleni Pitsillou

According to our database, Eleni Pitsillou authored at least 7 papers between 2020 and 2022.

Collaborative distances:

• Dijkstra number of four.
• Erdős number of five.

2022

Identification of novel bioactive compounds from <i>Olea europaea</i> by evaluation of chemical compounds in the OliveNet™ library: <i>in silico</i> bioactivity and molecular modelling, and <i>in vitro</i> validation of hERG activity.

Eleni Pitsillou, Julia Liang, Raymond C. Beh, Jacqueline Prestedge, Seda Catak, Andrew Hung, Tom C. Karagiannis

Comput. Biol. Medicine, 2022

Molecular dynamics simulations highlight the altered binding landscape at the spike-ACE2 interface between the Delta and Omicron variants compared to the SARS-CoV-2 original strain.

Eleni Pitsillou, Julia Liang, Raymond C. Beh, Andrew Hung, Tom C. Karagiannis

Comput. Biol. Medicine, 2022

2020

Interaction of small molecules with the SARS-CoV-2 main protease <i>in silico</i> and <i>in vitro</i> validation of potential lead compounds using an enzyme-linked immunosorbent assay.

Eleni Pitsillou, Julia Liang, Chris Karagiannis, Katherine Ververis, Kevion K. Darmawan, Ken Ng, Andrew Hung, Tom C. Karagiannis

Comput. Biol. Chem., 2020

Molecular docking utilising the OliveNet™ library reveals novel phenolic compounds which may potentially target key proteins associated with major depressive disorder.

Eleni Pitsillou, Julia Liang, Andrew Hung, Tom C. Karagiannis

Comput. Biol. Chem., 2020

Utilisation of the OliveNet™ Library to investigate phenolic compounds using molecular modelling studies in the context of Alzheimer's disease.

Julia Liang, Eleni Pitsillou, Abella Y. L. Man, Sibonginkosi Madzima, Sarah M. Bresnehan, Michael E. Nakai, Andrew Hung, Tom C. Karagiannis

Comput. Biol. Chem., 2020

Interaction of the prototypical α-ketoamide inhibitor with the SARS-CoV-2 main protease active site in silico: Molecular dynamic simulations highlight the stability of the ligand-protein complex.

Julia Liang, Eleni Pitsillou, Chris Karagiannis, Kevion K. Darmawan, Ken Ng, Andrew Hung, Tom C. Karagiannis

Comput. Biol. Chem., 2020

Site mapping and small molecule blind docking reveal a possible target site on the SARS-CoV-2 main protease dimer interface.

Julia Liang, Chris Karagiannis, Eleni Pitsillou, Kevion K. Darmawan, Ken Ng, Andrew Hung, Tom C. Karagiannis

Comput. Biol. Chem., 2020