Glen E. P. Ropella

According to our database1, Glen E. P. Ropella authored at least 20 papers between 2004 and 2020.

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Bibliography

2020
Contrasting model mechanisms of alanine aminotransferase (ALT) release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms.
PLoS Comput. Biol., 2020

2016
Competing Mechanistic Hypotheses of Acetaminophen-Induced Hepatotoxicity Challenged by Virtual Experiments.
PLoS Comput. Biol., 2016

Open-Ended Evolution: Perspectives from the OEE Workshop in York.
Artif. Life, 2016

Virtual experiments help explain intra- and inter-strain variability of AILI-induced hepatic necrosis in mice.
Proceedings of the Agent-Directed Simulation Symposium, 2016

Measuring analog granularity.
Proceedings of the Agent-Directed Simulation Symposium, 2016

Implementing a cell-centered, agent-based framework with flexible environment granularities using MASON and VTK.
Proceedings of the Agent-Directed Simulation Symposium, 2016

2014
Toward modular biological models: defining analog modules based on referent physiological mechanisms.
BMC Syst. Biol., 2014

Mechanistic agent-based damage and repair models as hypotheses for patterns of necrosis caused by drug induced liver injury.
Proceedings of the 2014 Summer Simulation Multiconference, 2014

2012
Falsifying an Enzyme Induction Mechanism within a Validated, Multiscale Liver Model.
Int. J. Agent Technol. Syst., 2012

Zonation of drug-induced, hepatic enzyme induction: falsifying fine grained mechanisms within a validated, multiscale In Silico Liver.
Proceedings of the 2012 Spring Simulation Multiconference, 2012

2010
Agent-Directed Tracing of Multi-Scale Drug Disposition Events within Normal and Diseased In Silico Livers.
Int. J. Agent Technol. Syst., 2010

Cloud computing and validation of expandable in silico livers.
BMC Syst. Biol., 2010

Agent-based simulation of drug disposition in cirrhotic liver.
Proceedings of the 2010 Spring Simulation Multiconference, 2010

2009
Evaluating an hepatic enzyme induction mechanism through coarse- and fine-grained measurements of an in silico liver.
Complex., 2009

Focus on discovering mechanisms: a relativistic, agent-directed, perfused liver.
Proceedings of the 2009 Spring Simulation Multiconference, SpringSim 2009, 2009

2008
Essential operating principles for tumor spheroid growth.
BMC Syst. Biol., 2008

Predicting hepatic disposition properties of cationic drugs using a physiologically based, agent-oriented In Silico Liver.
Proceedings of the 2008 Spring Simulation Multiconference, 2008

2007
Tracking Compounds and Their Interactions within In Silico Liver.
Proceedings of the ISCA 20th International Conference on Computer Applications in Industry and Engineering, 2007

Affects of Surface Detection on Shape and Growth of Model Tumor Spheroids.
Proceedings of the ISCA 20th International Conference on Computer Applications in Industry and Engineering, 2007

2004
Biomimetic in Silico Devices.
Proceedings of the Computational Methods in Systems Biology, International Conference, 2004


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