Guo-Bo Li

According to our database, Guo-Bo Li authored at least 10 papers between 2013 and 2025.

Collaborative distances:

• Dijkstra number of five.
• Erdős number of four.

2025

A 3D pocket-aware and evolutionary conserved interaction guided diffusion model for molecular optimization.

Anjie Qiao, Hao Zhang, Qianmu Yuan, Qirui Deng, Jingtian Su, Weifeng Huang, Huihao Zhou, Guo-Bo Li, Zhen Wang, Jinping Lei

CoRR, May, 2025

A 3D pocket-aware and affinity-guided diffusion model for lead optimization.

Anjie Qiao, Junjie Xie, Weifeng Huang, Hao Zhang, Jiahua Rao, Shuangjia Zheng, Yuedong Yang, Zhen Wang, Guo-Bo Li, Jinping Lei

CoRR, April, 2025

Deciphering Glutaminyl Cyclase Catalytic Pathways Enables Recognition of Anchor Pharmacophores for Inhibitor Discovery.

Jing-Wei Wu, Xiang-Li Ning, Biao-Dan Tang, Yi-Ting Chen, Zeng-Bao Yang, Fan-Bo Meng, Cong Zhou, Jun-Lin Yu, Rong Li, Zhe Li, Guo-Bo Li

J. Chem. Inf. Model., 2025

A 3D pocket-aware lead optimization model with knowledge guidance and its application for discovery of new glutaminyl cyclase inhibitors.

Anjie Qiao, Yuting Chen, Junjie Xie, Weifeng Huang, Hao Zhang, Qirui Deng, Jiahua Rao, Ji Deng, Fanbo Meng, Zhen Wang, Mingyuan Xu, Hongming Chen, Jiancong Xie, Shuangjia Zheng, Yuedong Yang, Guo-Bo Li, Jinping Lei

Briefings Bioinform., 2025

2023

MeDBA: the Metalloenzyme Data Bank and Analysis platform.

Jun-Lin Yu, Song Wu, Cong Zhou, Qing-Qing Dai, Christopher J. Schofield, Guo-Bo Li

Nucleic Acids Res., January, 2023

2022

MeCOM: A Method for Comparing Three-Dimensional Metalloenzyme Active Sites.

Gen Li, Qing-Qing Dai, Guo-Bo Li

J. Chem. Inf. Model., 2022

2020

MeLAD: an integrated resource for metalloenzyme-ligand associations.

Gen Li, Yu Su, Yuhang Yan, Jiayi Peng, Qing-Qing Dai, Xiang-Li Ning, Cheng-Long Zhu, Chen Fu, Michael A. McDonough, Christopher J. Schofield, Cheng Huang, Guo-Bo Li

Bioinform., 2020

2017

IFPTarget: A Customized Virtual Target Identification Method Based on Protein-Ligand Interaction Fingerprinting Analyses.

Guo-Bo Li, Zhu-Jun Yu, Sha Liu, Lu-Yi Huang, Ling-Ling Yang, Christopher T. Lohans, Sheng-Yong Yang

J. Chem. Inf. Model., July, 2017

2014

A prediction model of drug-induced ototoxicity developed by an optimal support vector machine (SVM) method.

Shu Zhou, Guo-Bo Li, Lu-Yi Huang, Huan-Zhang Xie, Ying-Lan Zhao, Yuzong Chen, Lin-Li Li, Sheng-Yong Yang

Comput. Biol. Medicine, 2014

2013

ID-Score: A New Empirical Scoring Function Based on a Comprehensive Set of Descriptors Related to Protein-Ligand Interactions.

Guo-Bo Li, Ling-Ling Yang, Wen-Jing Wang, Lin-Li Li, Sheng-Yong Yang

J. Chem. Inf. Model., 2013