Jinping Lei

According to our database, Jinping Lei authored at least 8 papers between 2022 and 2025.

Collaborative distances:

• Dijkstra number of four.
• Erdős number of four.

2025

A 3D pocket-aware and evolutionary conserved interaction guided diffusion model for molecular optimization.

Anjie Qiao, Hao Zhang, Qianmu Yuan, Qirui Deng, Jingtian Su, Weifeng Huang, Huihao Zhou, Guo-Bo Li, Zhen Wang, Jinping Lei

CoRR, May, 2025

A 3D pocket-aware and affinity-guided diffusion model for lead optimization.

Anjie Qiao, Junjie Xie, Weifeng Huang, Hao Zhang, Jiahua Rao, Shuangjia Zheng, Yuedong Yang, Zhen Wang, Guo-Bo Li, Jinping Lei

CoRR, April, 2025

Systematic Parameter Decision in Approximate Model Counting.

Jinping Lei, Toru Takisaka, Junqiang Peng, Mingyu Xiao

CoRR, April, 2025

A 3D pocket-aware lead optimization model with knowledge guidance and its application for discovery of new glutaminyl cyclase inhibitors.

Anjie Qiao, Yuting Chen, Junjie Xie, Weifeng Huang, Hao Zhang, Qirui Deng, Jiahua Rao, Ji Deng, Fanbo Meng, Zhen Wang, Mingyuan Xu, Hongming Chen, Jiancong Xie, Shuangjia Zheng, Yuedong Yang, Guo-Bo Li, Jinping Lei

Briefings Bioinform., 2025

2024

GRELinker: A Graph-Based Generative Model for Molecular Linker Design with Reinforcement and Curriculum Learning.

Hao Zhang, Jinchao Huang, Junjie Xie, Weifeng Huang, Yuedong Yang, Mingyuan Xu, Jinping Lei, Hongming Chen

J. Chem. Inf. Model., 2024

DiffDec: Structure-Aware Scaffold Decoration with an End-to-End Diffusion Model.

Junjie Xie, Sheng Chen, Jinping Lei, Yuedong Yang

J. Chem. Inf. Model., 2024

How Good are Current Pocket-Based 3D Generative Models?: The Benchmark Set and Evaluation of Protein Pocket-Based 3D Molecular Generative Models.

Haoyang Liu, Yifei Qin, Zhangming Niu, Mingyuan Xu, Jiaqiang Wu, Xianglu Xiao, Jinping Lei, Ting Ran, Hongming Chen

J. Chem. Inf. Model., 2024

2022

DRlinker: Deep Reinforcement Learning for Optimization in Fragment Linking Design.

Youhai Tan, Lingxue Dai, Weifeng Huang, Yinfeng Guo, Shuangjia Zheng, Jinping Lei, Hongming Chen, Yuedong Yang

J. Chem. Inf. Model., 2022