Steffen Lindert

According to our database, Steffen Lindert authored at least 15 papers between 2012 and 2024.

Collaborative distances:

• Dijkstra number of five.
• Erdős number of five.

2024

Discovery of Nanomolar Inhibitors for Human Dihydroorotate Dehydrogenase Using Structure-Based Drug Discovery Methods.

William T. Higgins, Sandip Vibhute, Chad Bennett, Steffen Lindert

J. Chem. Inf. Model., 2024

2023

Predicting ion mobility collision cross sections using projection approximation with ROSIE-PARCS webserver.

S. M. Bargeen Alam Turzo, Justin T. Seffernick, Sergey Lyskov, Steffen Lindert

Briefings Bioinform., September, 2023

Targeting Troponin C with Small Molecules Containing Diphenyl Moieties: Calcium Sensitivity Effects on Striated Muscles and Structure-Activity Relationship.

Eric R. Hantz, Svetlana B. Tikunova, Natalya Belevych, Jonathan P. Davis, Peter J. Reiser, Steffen Lindert

J. Chem. Inf. Model., June, 2023

Umbrella Sampling Simulations of Cardiac Thin Filament Reveal Thermodynamic Consequences of Troponin I Inhibitory Peptide Mutations.

Austin M. Cool, Steffen Lindert

J. Chem. Inf. Model., June, 2023

2022

Computational Exploration and Characterization of Potential Calcium Sensitizing Mutations in Cardiac Troponin C.

Eric R. Hantz, Steffen Lindert

J. Chem. Inf. Model., 2022

Actives-Based Receptor Selection Strongly Increases the Success Rate in Structure-Based Drug Design and Leads to Identification of 22 Potent Cancer Inhibitors.

Eric R. Hantz, Steffen Lindert

J. Chem. Inf. Model., 2022

Umbrella Sampling Simulations Measure Switch Peptide Binding and Hydrophobic Patch Opening Free Energies in Cardiac Troponin.

Austin M. Cool, Steffen Lindert

J. Chem. Inf. Model., 2022

2021

Adaptative Steered Molecular Dynamics Study of Mutagenesis Effects on Calcium Affinity in the Regulatory Domain of Cardiac Troponin C.

Eric R. Hantz, Steffen Lindert

J. Chem. Inf. Model., 2021

2020

Using NMR Chemical Shifts and Cryo-EM Density Restraints in Iterative Rosetta-MD Protein Structure Refinement.

Sumudu P. Leelananda, Steffen Lindert

J. Chem. Inf. Model., 2020

Discovery of Novel Small-Molecule Calcium Sensitizers for Cardiac Troponin C: A Combined Virtual and Experimental Screening Approach.

William H. Coldren, Svetlana B. Tikunova, Jonathan P. Davis, Steffen Lindert

J. Chem. Inf. Model., 2020

2019

Mechanism of Cardiac Troponin C Calcium Sensitivity Modulation by Small Molecules Illuminated by Umbrella Sampling Simulations.

Jacob D. Bowman, William H. Coldren, Steffen Lindert

J. Chem. Inf. Model., 2019

2017

Successful Identification of Cardiac Troponin Calcium Sensitizers Using a Combination of Virtual Screening and ROC Analysis of Known Troponin C Binders.

Melanie L. Aprahamian, Svetlana B. Tikunova, Morgan V. Price, Andres F. Cuesta, Jonathan P. Davis, Steffen Lindert

J. Chem. Inf. Model., December, 2017

2015

In silico screening for Plasmodium falciparum enoyl-ACP reductase inhibitors.

Steffen Lindert, Lorillee Tallorin, Quynh G. Nguyen, Michael D. Burkart, James Andrew McCammon

J. Comput. Aided Mol. Des., 2015

2013

Computational determination of the orientation of a heat repeat-like domain of DNA-PKcs.

Steffen Lindert, Phoebe L. Stewart, Jens Meiler

Comput. Biol. Chem., 2013

2012

Molecular Basis of Calcium-Sensitizing and Desensitizing Mutations of the Human Cardiac Troponin C Regulatory Domain: A Multi-Scale Simulation Study.

Peter Michael Kekenes-Huskey, Steffen Lindert, James Andrew McCammon

PLoS Comput. Biol., 2012