George M. Spyrou
Orcid: 0000-0002-2470-3363
According to our database1,
George M. Spyrou
authored at least 54 papers
between 2001 and 2023.
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Bibliography
2023
Vir2Drug: a drug repurposing framework based on protein similarities between pathogens.
Briefings Bioinform., January, 2023
2021
Performance evaluation of pipelines for mapping, variant calling and interval padding, for the analysis of NGS germline panels.
BMC Bioinform., 2021
Multi-omics data integration and network-based analysis drives a multiplex drug repurposing approach to a shortlist of candidate drugs against COVID-19.
Briefings Bioinform., 2021
Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches.
Briefings Bioinform., 2021
Computational insights on the molecular mechanisms across breast cancer progression combining gene differential expression and co-expression.
Proceedings of the IEEE EMBS International Conference on Biomedical and Health Informatics, 2021
2020
PathWalks: identifying pathway communities using a disease-related map of integrated information.
Bioinform., 2020
ChemBioServer 2.0: an advanced web server for filtering, clustering and networking of chemical compounds facilitating both drug discovery and repurposing.
Bioinform., 2020
2019
Revealing Clusters of Connected Pathways Through Multisource Data Integration in Huntington's Disease and Spastic Ataxia.
IEEE J. Biomed. Health Informatics, 2019
Pattern Recognit., 2019
Bioinform., 2019
Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches.
Briefings Bioinform., 2019
Computational profiling of the gut-brain axis: microflora dysbiosis insights to neurological disorders.
Briefings Bioinform., 2019
In Silico Assessment of the Structural, Functional and Stability Impact of a Nonsense PRF1 Mutation with Uncertain Clinical Significance; Identified in 2 Unrelated Cypriot Triple-Negative Breast Cancer Patients.
Proceedings of the 19th IEEE International Conference on Bioinformatics and Bioengineering, 2019
Design and Initial Implementation of a Computer Aided Diagnosis System for PET/CT Solitary Pulmonary Nodule Risk Estimation.
Proceedings of the 19th IEEE International Conference on Bioinformatics and Bioengineering, 2019
Exploring Fibrotic Disease Networks to Identify Common Molecular Mechanisms with IPF.
Proceedings of the 19th IEEE International Conference on Bioinformatics and Bioengineering, 2019
The Effect of a Spastic Ataxia Associated GBA2 Mutation on Protein-Protein Interactions and Pathways.
Proceedings of the 19th IEEE International Conference on Bioinformatics and Bioengineering, 2019
Computational Identification of Metabolites for Pathways Related to Huntington's Disease.
Proceedings of the 19th IEEE International Conference on Bioinformatics and Bioengineering, 2019
2017
D-Map: Random Walking on Gene Network Inference Maps Towards differential Avenue Discovery.
IEEE ACM Trans. Comput. Biol. Bioinform., 2017
Automatic cumulative sums contour detection of FBP-reconstructed multi-object nuclear medicine images.
Comput. Biol. Medicine, 2017
BMC Syst. Biol., 2017
2016
SPNsim: A database of simulated solitary pulmonary nodule PET/CT images facilitating computer aided diagnosis.
J. Biomed. Informatics, 2016
Briefings Bioinform., 2016
2015
A CAD$_{\bf x}$ Scheme for Mammography Empowered With Topological Information From Clustered Microcalcifications' Atlases.
IEEE J. Biomed. Health Informatics, 2015
IEEE ACM Trans. Comput. Biol. Bioinform., 2015
mAPKL: R/ Bioconductor package for detecting gene exemplars and revealing their characteristics.
BMC Bioinform., 2015
GeneStoryTeller: a mobile app for quick and comprehensive information retrieval of human genes.
Database J. Biol. Databases Curation, 2015
2014
A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools.
Database J. Biol. Databases Curation, 2014
2013
BiDaS: a web-based Monte Carlo BioData Simulator based on sequence/feature characteristics.
Nucleic Acids Res., 2013
Proceedings of the 13th IEEE International Conference on BioInformatics and BioEngineering, 2013
Proceedings of the 13th IEEE International Conference on BioInformatics and BioEngineering, 2013
Performance evaluation of clustering algorithms on microcalcifications as mammography findings.
Proceedings of the 13th IEEE International Conference on BioInformatics and BioEngineering, 2013
Variations on breast density and subtlety of the findings require different computational intelligence pipelines for the diagnosis of clustered microcalcifications.
Proceedings of the 13th IEEE International Conference on BioInformatics and BioEngineering, 2013
Proceedings of the 13th IEEE International Conference on BioInformatics and BioEngineering, 2013
2012
Combining multiple hypothesis testing and affinity propagation clustering leads to accurate, robust and sample size independent classification on gene expression data.
BMC Bioinform., 2012
ChemBioServer: a web-based pipeline for filtering, clustering and visualization of chemical compounds used in drug discovery.
Bioinform., 2012
Proceedings of the 12th IEEE International Conference on Bioinformatics & Bioengineering, 2012
Enhancing the effectiveness of virtual screening by using the ChemBioServer: Application to the discovery of PI3Kα inhibitors.
Proceedings of the 12th IEEE International Conference on Bioinformatics & Bioengineering, 2012
e-Prolipsis: A web based risk estimation platform to support and register breast cancer diagnosis in Greece.
Proceedings of the 12th IEEE International Conference on Bioinformatics & Bioengineering, 2012
2011
Investigating the Minimum Required Number of Genes for the Classification of Neuromuscular Disease Microarray Data.
IEEE Trans. Inf. Technol. Biomed., 2011
Nucleic Acids Res., 2011
2010
A similarity network approach for the analysis and comparison of protein sequence/structure sets.
J. Biomed. Informatics, 2010
Studying the properties of the updating coefficients in the OSEM algorithm for iterative image reconstruction in PET.
Comput. Methods Programs Biomed., 2010
PET image reconstruction: A stopping rule for the MLEM algorithm based on properties of the updating coefficients.
Comput. Medical Imaging Graph., 2010
Downgrading BIRADS 3 to BIRADS 2 category using a computer-aided microcalcification analysis and risk assessment system for early breast cancer.
Comput. Biol. Medicine, 2010
2009
Bioinform., 2009
Proceedings of the Medical Informatics in a United and Healthy Europe - Proceedings of MIE 2009, The XXIInd International Congress of the European Federation for Medical Informatics, Sarajevo, Bosnia and Herzegovina, August 30, 2009
2008
Bioinform., 2008
Protein similarity networks and Genetic Algorithm driven feature selection for fold recognition.
Proceedings of the 8th IEEE International Conference on Bioinformatics and Bioengineering, 2008
A high throughput approach to keep alive a web-based database system for multiple search among published bioinformatics tools and databases.
Proceedings of the 8th IEEE International Conference on Bioinformatics and Bioengineering, 2008
2007
Genom. Proteom. Bioinform., 2007
2006
"Hippocrates-mst": a prototype for computer-aided microcalcification analysis and risk assessment for breast cancer.
Medical Biol. Eng. Comput., 2006
Proceedings of the Ubiquity: Technologies for Better Health in Aging Societies, 2006
Study on Preprocessing and Classifying Mass Spectral Raw Data Concerning Human Normal and Disease Cases.
Proceedings of the Biological and Medical Data Analysis, 7th International Symposium, 2006
2001
Development of a simulation algorithm for mammographic imaging based on Monte Carlo methods
PhD thesis, 2001