Antti Poso

According to our database, Antti Poso authored at least 22 papers between 2001 and 2024.

Collaborative distances:

• Dijkstra number of four.
• Erdős number of four.

2024

Aminopyrimidine Derivatives as Multiflavivirus Antiviral Compounds Identified from a Consensus Virtual Screening Approach.

Mateus Sá Magalhães Serafim, Thales Kronenberger, Rafael Eduardo Oliveira Rocha, Amanda Del Rio Abreu Rosa, Thaysa Lara Gonçalves Mello, Antti Poso, Rafaela Salgado Ferreira, Jonatas Santos Abrahão, Erna Geessien Kroon, Bruno Eduardo Fernandes Mota, Vinicius Gonçalves Maltarollo

J. Chem. Inf. Model., 2024

2023

Machine Learning-Boosted Docking Enables the Efficient Structure-Based Virtual Screening of Giga-Scale Enumerated Chemical Libraries.

Toni Sivula, Laxman Yetukuri, Tuomo Kalliokoski, Heikki Käsnänen, Antti Poso, Ina Pöhner

J. Chem. Inf. Model., September, 2023

2022

Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease M^pro and Papain-like Protease PL^pro of SARS-CoV-2.

Lucianna Helene Santos, Thales Kronenberger, Renata G. Almeida, Elany B. Silva, Rafael E. O. Rocha, Joyce C. Oliveira, Luiza V. Barreto, Danielle Skinner, Pavla Fajtová, Miriam A. Giardini, Brendon Woodworth, Conner Bardine, André L. Lourenço, Charles S. Craik, Antti Poso, Larissa M. Podust, James H. McKerrow, Jair L. Siqueira-Neto, Anthony J. O'Donoghue, Eufrânio N. da Silva Júnior, Rafaela Salgado Ferreira

J. Chem. Inf. Model., 2022

Do Go Chasing Waterfalls: Enoyl Reductase (FabI) in Complex with Inhibitors Stabilizes the Tetrameric Structure and Opens Water Channels.

Vinicius Gonçalves Maltarollo, Ekaterina Shevchenko, Igor Daniel de Miranda Lima, Elio A. Cino, Glaucio Monteiro Ferreira, Antti Poso, Thales Kronenberger

J. Chem. Inf. Model., 2022

Structure of POPC Lipid Bilayers in OPLS3e Force Field.

Milla Kurki, Antti Poso, Piia Bartos, Markus S. Miettinen

J. Chem. Inf. Model., 2022

2021

Structural Characterization of LsrK as a Quorum Sensing Target and a Comparison between X-ray and Homology Models.

Prasanthi Medarametla, Thales Kronenberger, Tuomo Laitinen, Antti Poso

J. Chem. Inf. Model., 2021

2020

DeepCDA: deep cross-domain compound-protein affinity prediction through LSTM and convolutional neural networks.

Karim Abbasi, Parvin Razzaghi, Antti Poso, Massoud Amanlou, Jahan B. Ghasemi, Ali Masoudi-Nejad

Bioinform., 2020

2019

Deep Transferable Compound Representation across Domains and Tasks for Low Data Drug Discovery.

Karim Abbasi, Antti Poso, Jahan B. Ghasemi, Massoud Amanlou, Ali Masoudi-Nejad

J. Chem. Inf. Model., 2019

2018

Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling.

Tatu Pantsar, Sami Rissanen, Daniel Dauch, Tuomo Laitinen, Ilpo Vattulainen, Antti Poso

PLoS Comput. Biol., 2018

2014

Integrative and Personalized QSAR Analysis in Cancer by Kernelized Bayesian Matrix Factorization.

Muhammad Ammad-ud-din, Elisabeth Georgii, Mehmet Gönen, Tuomo Laitinen, Olli-P. Kallioniemi, Krister Wennerberg, Antti Poso, Samuel Kaski

J. Chem. Inf. Model., 2014

Identification of structural features in chemicals associated with cancer drug response: a systematic data-driven analysis.

Suleiman A. Khan, Seppo Virtanen, Olli-P. Kallioniemi, Krister Wennerberg, Antti Poso, Samuel Kaski

Bioinform., 2014

2012

Molecular Dynamics Simulations for Human CAR Inverse Agonists.

Johanna Jyrkkärinne, Jenni Küblbeck, Juha Pulkkinen, Paavo Honkakoski, Reino Laatikainen, Antti Poso, Tuomo Laitinen

J. Chem. Inf. Model., 2012

Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs.

Suleiman A. Khan, Ali Faisal, John Mpindi, Juuso A. Parkkinen, Tuomo Kalliokoski, Antti Poso, Olli-P. Kallioniemi, Krister Wennerberg, Samuel Kaski

BMC Bioinform., 2012

2009

Critical Comparison of Virtual Screening Methods against the MUV Data Set.

Pekka Tiikkainen, Patrick Markt, Gerhard Wolber, Johannes Kirchmair, Simona Distinto, Antti Poso, Olli-P. Kallioniemi

J. Chem. Inf. Model., 2009

The Effect of Ligand-Based Tautomer and Protomer Prediction on Structure-Based Virtual Screening.

Tuomo Kalliokoski, Heikki S. Salo, Maija Lahtela-Kakkonen, Antti Poso

J. Chem. Inf. Model., 2009

Comparison of structure fingerprint and molecular interaction field based methods in explaining biological similarity of small molecules in cell-based screens.

Pekka Tiikkainen, Antti Poso, Olli-P. Kallioniemi

J. Comput. Aided Mol. Des., 2009

2008

FieldChopper, A New Tool for Automatic Model Generation and Virtual Screening Based on Molecular Fields.

Tuomo Kalliokoski, Toni Rönkkö, Antti Poso

J. Chem. Inf. Model., 2008

2006

BRUTUS: Optimization of a grid-based similarity function for rigid-body molecular superposition. II. Description and characterization.

Toni Rönkkö, Anu J. Tervo, Jussi Parkkinen, Antti Poso

J. Comput. Aided Mol. Des., 2006

Comparative and pharmacophore model for deacetylase SIRT1.

Tero Huhtiniemi, Carsten Wittekindt, Tuomo Laitinen, Jukka Leppänen, Antero Salminen, Antti Poso, Maija Lahtela-Kakkonen

J. Comput. Aided Mol. Des., 2006

2004

Comparing the Quality and Predictiveness between 3D QSAR Models Obtained from Manual and Automated Alignment.

Anu J. Tervo, Tommi H. Nyrönen, Toni Rönkkö, Antti Poso

J. Chem. Inf. Model., 2004

2003

A structure-activity relationship study of catechol-O-methyltransferase inhibitors combining molecular docking and 3D QSAR methods.

Anu J. Tervo, Tommi H. Nyrönen, Toni Rönkkö, Antti Poso

J. Comput. Aided Mol. Des., 2003

2001

A comparative molecular field analysis of cytochrome P450 2A5 and 2A6 inhibitors.

Antti Poso, Jukka Gynther, Risto Juvonen

J. Comput. Aided Mol. Des., 2001