Nicholas Furnham

According to our database, Nicholas Furnham authored at least 12 papers between 2011 and 2024.

Collaborative distances:

• Dijkstra number of five.
• Erdős number of four.

2024

Optimisation-based modelling for explainable lead discovery in malaria.

Yutong Li, Jonathan Cardoso-Silva, John M. Kelly, Michael J. Delves, Nicholas Furnham, Lazaros G. Papageorgiou, Sophia Tsoka

Artif. Intell. Medicine, January, 2024

2018

Computationally-guided drug repurposing enables the discovery of kinase targets and inhibitors as new schistosomicidal agents.

Sandra Giuliani, Arthur C. Silva, Joyce V. V. B. Borba, Pablo I. P. Ramos, Ross A. Paveley, Eugene N. Muratov, Carolina Horta Andrade, Nicholas Furnham

PLoS Comput. Biol., 2018

Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites.

António J. M. Ribeiro, Gemma L. Holliday, Nicholas Furnham, Jonathan D. Tyzack, Katherine Ferris, Janet M. Thornton

Nucleic Acids Res., 2018

2016

FunTree: advances in a resource for exploring and contextualising protein function evolution.

Ian Sillitoe, Nicholas Furnham

Nucleic Acids Res., 2016

QSAR-Driven Discovery of Novel Chemical Scaffolds Active against <i>Schistosoma mansoni</i>.

Cleber C. Melo-Filho, Rafael Ferreira Dantas, Rodolpho C. Braga, Bruno Junior Neves, Mario R. Senger, Walter C. G. Valente, João M. Rezende-Neto, Willian T. Chaves, Eugene N. Muratov, Ross A. Paveley, Nicholas Furnham, Lee Kamentsky, Anne E. Carpenter, Floriano Silva-Junior, Carolina Horta Andrade

J. Chem. Inf. Model., 2016

2015

Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity.

Nidhi Tyagi, Edward J. Farnell, Colin M. Fitzsimmons, Stephanie Ryan, Edridah M. Tukahebwa, Rick M. Maizels, David W. Dunne, Janet M. Thornton, Nicholas Furnham

PLoS Comput. Biol., 2015

CATH: comprehensive structural and functional annotations for genome sequences.

Ian Sillitoe, Tony E. Lewis, Alison L. Cuff, Sayoni Das, Paul Ashford, Natalie L. Dawson, Nicholas Furnham, Roman A. Laskowski, David A. Lee, Jonathan G. Lees, Sonja Lehtinen, Romain A. Studer, Janet M. Thornton, Christine A. Orengo

Nucleic Acids Res., 2015

2014

The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes.

Nicholas Furnham, Gemma L. Holliday, Tjaart A. P. de Beer, Julius O. B. Jacobsen, William R. Pearson, Janet M. Thornton

Nucleic Acids Res., 2014

2013

New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures.

Ian Sillitoe, Alison L. Cuff, Benoit H. Dessailly, Natalie L. Dawson, Nicholas Furnham, David A. Lee, Jonathan G. Lees, Tony E. Lewis, Romain A. Studer, Robert Rentzsch, Corin Yeats, Janet M. Thornton, Christine A. Orengo

Nucleic Acids Res., 2013

2012

Exploring the Evolution of Novel Enzyme Functions within Structurally Defined Protein Superfamilies.

Nicholas Furnham, Ian Sillitoe, Gemma L. Holliday, Alison L. Cuff, Roman A. Laskowski, Christine A. Orengo, Janet M. Thornton

PLoS Comput. Biol., 2012

FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies.

Nicholas Furnham, Ian Sillitoe, Gemma L. Holliday, Alison L. Cuff, Syed Asad Rahman, Roman A. Laskowski, Christine A. Orengo, Janet M. Thornton

Nucleic Acids Res., 2012

2011

Extending CATH: increasing coverage of the protein structure universe and linking structure with function.

Alison L. Cuff, Ian Sillitoe, Tony E. Lewis, Andrew B. Clegg, Robert Rentzsch, Nicholas Furnham, Marialuisa Pellegrini-Calace, David T. Jones, Janet M. Thornton, Christine A. Orengo

Nucleic Acids Res., 2011