Isaac S. Kohane
Orcid: 0000-0003-2192-5160Affiliations:
- Harvard Medical School, Boston, MA, USA
According to our database1,
Isaac S. Kohane
authored at least 178 papers
between 1993 and 2023.
Collaborative distances:
Collaborative distances:
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on chip.org
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Bibliography
2023
Event Stream GPT: A Data Pre-processing and Modeling Library for Generative, Pre-trained Transformers over Continuous-time Sequences of Complex Events.
Proceedings of the Advances in Neural Information Processing Systems 36: Annual Conference on Neural Information Processing Systems 2023, 2023
2022
International electronic health record-derived post-acute sequelae profiles of COVID-19 patients.
npj Digit. Medicine, 2022
SurvMaximin: Robust federated approach to transporting survival risk prediction models.
J. Biomed. Informatics, 2022
Analytics to monitor local impact of the Protecting Access to Medicare Act's imaging clinical decision support requirements.
J. Am. Medical Informatics Assoc., 2022
Multi-PheWAS intersection approach to identify sex differences across comorbidities in 59 140 pediatric patients with autism spectrum disorder.
J. Am. Medical Informatics Assoc., 2022
Construction of extra-large scale screening tools for risks of severe mental illnesses using real world healthcare data.
CoRR, 2022
Identifying Heterogeneous Treatment Effects in Multiple Outcomes using Joint Confidence Intervals.
Proceedings of the Machine Learning for Health, 2022
Proceedings of the Challenges of Trustable AI and Added-Value on Health, 2022
2021
Machine learning for patient risk stratification: standing on, or looking over, the shoulders of clinicians?
npj Digit. Medicine, 2021
ATLAS: an automated association test using probabilistically linked health records with application to genetic studies.
J. Am. Medical Informatics Assoc., 2021
J. Am. Medical Informatics Assoc., 2021
Use of electronic health records to support a public health response to the COVID-19 pandemic in the United States: a perspective from 15 academic medical centers.
J. Am. Medical Informatics Assoc., 2021
Validation of an internationally derived patient severity phenotype to support COVID-19 analytics from electronic health record data.
J. Am. Medical Informatics Assoc., 2021
J. Am. Medical Informatics Assoc., 2021
Cross-modal representation alignment of molecular structure and perturbation-induced transcriptional profiles.
Proceedings of the Biocomputing 2021: Proceedings of the Pacific Symposium, 2021
Proceedings of the 59th Annual Meeting of the Association for Computational Linguistics and the 11th International Joint Conference on Natural Language Processing, 2021
2020
IEEE ACM Trans. Comput. Biol. Bioinform., 2020
International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium.
npj Digit. Medicine, 2020
Classifying non-small cell lung cancer types and transcriptomic subtypes using convolutional neural networks.
J. Am. Medical Informatics Assoc., 2020
An interactive online dashboard for tracking COVID-19 in U.S. counties, cities, and states in real time.
J. Am. Medical Informatics Assoc., 2020
Scalability and cost-effectiveness analysis of whole genome-wide association studies on Google Cloud Platform and Amazon Web Services.
J. Am. Medical Informatics Assoc., 2020
Meta-analysis of Caenorhabditis elegans single-cell developmental data reveals multi-frequency oscillation in gene activation.
Bioinform., 2020
Proceedings of the Pacific Symposium on Biocomputing 2020, 2020
Deciphering Serous Ovarian Carcinoma Histopathology and Platinum Response by Convolutional Neural Networks.
Proceedings of the AMIA 2020, 2020
2019
J. Biomed. Informatics, 2019
J. Biomed. Informatics, 2019
J. Am. Medical Informatics Assoc., 2019
Approaching Small Molecule Prioritization as a Cross-Modal Information Retrieval Task through Coordinated Representation Learning.
CoRR, 2019
Batch correction evaluation framework using a-priori gene-gene associations: applied to the GTEx dataset.
BMC Bioinform., 2019
Learning Contextual Hierarchical Structure of Medical Concepts with Poincairé Embeddings to Clarify Phenotypes.
Proceedings of the Biocomputing 2019: Proceedings of the Pacific Symposium, 2019
Classifying Non-Small Cell Lung Cancer Histopathology Types and Transcriptomic Subtypes using Convolutional Neural Networks.
Proceedings of the AMIA 2019, 2019
Proceedings of the AMIA 2019, 2019
2018
PheProb: probabilistic phenotyping using diagnosis codes to improve power for genetic association studies.
J. Am. Medical Informatics Assoc., 2018
CoRR, 2018
Rcupcake: an R package for querying and analyzing biomedical data through the BD2K PIC-SURE RESTful API.
Bioinform., 2018
High-Throughput Multimodal Automated Phenotyping (MAP) Incorporating Natural Language Processing with Application to PheWAS.
Proceedings of the AMIA 2018, 2018
2017
J. Am. Medical Informatics Assoc., 2017
Proceedings of the Summit on Clinical Research Informatics, 2017
Proceedings of the AMIA 2017, 2017
Proceedings of the AMIA 2017, 2017
2016
A model-driven methodology for exploring complex disease comorbidities applied to autism spectrum disorder and inflammatory bowel disease.
J. Biomed. Informatics, 2016
SMART precision cancer medicine: a FHIR-based app to provide genomic information at the point of care.
J. Am. Medical Informatics Assoc., 2016
SMART on FHIR: a standards-based, interoperable apps platform for electronic health records.
J. Am. Medical Informatics Assoc., 2016
BMC Bioinform., 2016
Developing an Algorithm to Detect Early Childhood Obesity in Two Tertiary Pediatric Medical Centers.
Appl. Clin. Inform., 2016
Proceedings of the Biocomputing 2016: Proceedings of the Pacific Symposium, 2016
Proceedings of the Biocomputing 2016: Proceedings of the Pacific Symposium, 2016
Proceedings of the AMIA 2016, 2016
The Spectrum of Insomnia-Associated Comorbidities in an Electronic Medical Records Cohort.
Proceedings of the AMIA 2016, 2016
2015
Increasing the efficiency of trial-patient matching: automated clinical trial eligibility Pre-screening for pediatric oncology patients.
BMC Medical Informatics Decis. Mak., 2015
Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources.
J. Am. Medical Informatics Assoc., 2015
J. Am. Medical Informatics Assoc., 2015
Demonstrating the Advantages of Applying Data Mining Techniques on Time-Dependent Electronic Medical Records.
Proceedings of the AMIA 2015, 2015
2014
Brief communication: Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS): Architecture.
J. Am. Medical Informatics Assoc., 2014
Are Meaningful Use Stage 2 certified EHRs ready for interoperability? Findings from the SMART C-CDA Collaborative.
J. Am. Medical Informatics Assoc., 2014
SecurityEmpire: Development and Evaluation of a Digital Game to Promote Cybersecurity Education.
Proceedings of the 2014 USENIX Summit on Gaming, 2014
Proceedings of the AMIA 2014, 2014
Informatics for Integrating Biology and the Bedside (I2b2) Clinical Trials (CT) Patient Ascertainment Suite.
Proceedings of the AMIA 2014, 2014
2013
Improved de-identification of physician notes through integrative modeling of both public and private medical text.
BMC Medical Informatics Decis. Mak., 2013
Toward More Transparent and Reproducible Omics Studies Through a Common Metadata Checklist and Data Publications.
Big Data, 2013
Proceedings of the AMIA 2013, 2013
Organization and Transformation of Next-Generation Sequencing Data for Use within i2b2.
Proceedings of the AMIA 2013, 2013
2012
Proc. Natl. Acad. Sci. USA, 2012
Technical desiderata for the integration of genomic data into Electronic Health Records.
J. Biomed. Informatics, 2012
The SMART Platform: early experience enabling substitutable applications for electronic health records.
J. Am. Medical Informatics Assoc., 2012
A translational engine at the national scale: informatics for integrating biology and the bedside.
J. Am. Medical Informatics Assoc., 2012
Quantifying the white blood cell transcriptome as an accessible window to the multiorgan transcriptome.
Bioinform., 2012
Integrating Substitutable Medical Apps, Reusable Technologies (SMART) in the i2b2 Platform.
Proceedings of the AMIA 2012, 2012
Proceedings of the AMIA 2012, 2012
Proceedings of the AMIA 2012, 2012
2011
Information Technology research challenges for healthcare: from discovery to delivery.
SIGHIT Rec., 2011
J. Biomed. Informatics, 2011
J. Am. Medical Informatics Assoc., 2011
J. Am. Medical Informatics Assoc., 2011
Automated validation of genetic variants from large databases: ensuring that variant references refer to the same genomic locations.
Bioinform., 2011
2010
Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2).
J. Am. Medical Informatics Assoc., 2010
BMC Syst. Biol., 2010
Proceedings of the 1st USENIX Workshop on Health Security and Privacy, 2010
2009
Application of Information Technology: The Shared Health Research Information Network (SHRINE): A Prototype Federated Query Tool for Clinical Data Repositories.
J. Am. Medical Informatics Assoc., 2009
Research Paper: Prediction of Chronic Obstructive Pulmonary Disease (COPD) in Asthma Patients Using Electronic Medical Records.
J. Am. Medical Informatics Assoc., 2009
Integration of heterogeneous expression data sets extends the role of the retinol pathway in diabetes and insulin resistance.
Bioinform., 2009
Proceedings of the 27th International Conference on Human Factors in Computing Systems, 2009
2008
J. Am. Medical Informatics Assoc., 2008
J. Am. Medical Informatics Assoc., 2008
Characterization of Patients who Suffer Asthma Exacerbations using Data Extracted from Electronic Medical Records.
Proceedings of the AMIA 2008, 2008
2007
Model Formulation: A Self-scaling, Distributed Information Architecture for Public Health, Research, and Clinical Care.
J. Am. Medical Informatics Assoc., 2007
Architecture of the Open-source Clinical Research Chart from Informatics for Integrating Biology and the Bedside.
Proceedings of the AMIA 2007, 2007
2006
BMC Bioinform., 2006
Bioinform., 2006
Dynamic Bayesian Networks in Modelling Cellular Systems: a Critical Appraisal on Simulated Data.
Proceedings of the 19th IEEE International Symposium on Computer-Based Medical Systems (CBMS 2006), 2006
Integration of the Personally Controlled Electronic Medical Record into a Regional and Data Exchange: A National Demonstration.
Proceedings of the AMIA 2006, 2006
Proceedings of the AMIA 2006, 2006
Proceedings of the AMIA 2006, 2006
2005
The MAPPER database: a multi-genome catalog of putative transcription factor binding sites.
Nucleic Acids Res., 2005
Model Formulation: The PING Personally Controlled Electronic Medical Record System: Technical Architecture.
J. Am. Medical Informatics Assoc., 2005
Position Paper: Wireless Technology Infrastructures for Authentication of Patients: PKI that Rings.
J. Am. Medical Informatics Assoc., 2005
J. Am. Medical Informatics Assoc., 2005
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks.
BMC Bioinform., 2005
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes.
BMC Bioinform., 2005
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in cancer-associated gene expression measurements.
BMC Bioinform., 2005
CrossChip: a system supporting comparative analysis of different generations of Affymetrix arrays.
Bioinform., 2005
DITTO - a Tool for Identification of Patient Cohorts from the Text of Physician Notes in the Electronic Medical Record.
Proceedings of the AMIA 2005, 2005
Reverse Geocoding: Concerns about Patient Confidentiality in the Display of Geospatial Health Data.
Proceedings of the AMIA 2005, 2005
2004
Application of Information Technology: The Asthma Kiosk: A Patient-centered Technology for Collaborative Decision Support in the Emergency Department.
J. Am. Medical Informatics Assoc., 2004
White Paper: Training the Next Generation of Informaticians: The Impact of "BISTI" and Bioinformatics - A Report from the American College of Medical Informatics.
J. Am. Medical Informatics Assoc., 2004
BMC Bioinform., 2004
BMC Bioinform., 2004
A Submission Model for Use in the Indexing, Searching, and Retrieval of Distributed Pathology Case and Tissue Specimens.
Proceedings of the MEDINFO 2004, 2004
2003
BMC Bioinform., 2003
PGAGENE: integrating quantitative gene-specific results from the NHLBI Programs for Genomic Applications.
Bioinform., 2003
Human Genome Variation: Haplotypes, Linkage Disequilibrium, and Populations - Session Introduction.
Proceedings of the 8th Pacific Symposium on Biocomputing, 2003
Localization and Characterization of Mouse-Human Alignments Within the Human Genome. Does Evolutionary Conservation Suggest Functional Importance?
Proceedings of the AMIA 2003, 2003
2002
Visualization and evaluation of clusters for exploratory analysis of gene expression data.
J. Biomed. Informatics, 2002
Brief Review: The Contributions of Biomedical Informatics to the Fight Against Bioterrorism.
J. Am. Medical Informatics Assoc., 2002
Bioinform., 2002
Bioinform., 2002
Human Genome Variation: Disease, Drug Response, and Clinical Phenotypes - Session Introduction.
Proceedings of the 7th Pacific Symposium on Biocomputing, 2002
Linking gene expression data with patient survival times using partial least squares.
Proceedings of the Tenth International Conference on Intelligent Systems for Molecular Biology, 2002
Proceedings of the AMIA 2002, 2002
Proceedings of the AMIA 2002, 2002
Proceedings of the AMIA 2002, 2002
Proceedings of the AMIA 2002, 2002
Proceedings of the AMIA 2002, 2002
Computerized reminders to physicians in the emergency department: a web-based system to report late-arriving abnormal laboratory results.
Proceedings of the AMIA 2002, 2002
2001
Comparing the Similarity of Time-Series Gene Expression Using Signal Processing Metrics.
J. Biomed. Informatics, 2001
Human Genome Variation: Linking Genotypes to Clinical Phenotypes - Session Introduction.
Proceedings of the 6th Pacific Symposium on Biocomputing, 2001
Proceedings of the 6th Pacific Symposium on Biocomputing, 2001
Proceedings of the 6th Pacific Symposium on Biocomputing, 2001
Proceedings of the 6th Pacific Symposium on Biocomputing, 2001
Proceedings of the MEDINFO 2001, 2001
Evolution strategy applied to global optimization of clusters in gene expression data of DNA microarrays.
Proceedings of the 2001 Congress on Evolutionary Computation, 2001
Proceedings of the AMIA 2001, 2001
Proceedings of the AMIA 2001, 2001
2000
Application of Information Technology: Temporal Expressiveness in Querying a Time-stamp - based Clinical Database.
J. Am. Medical Informatics Assoc., 2000
J. Am. Medical Informatics Assoc., 2000
Implementation of an electronic medical record system in a pediatric psychopharmacology program.
Int. J. Medical Informatics, 2000
Multiple signal integration by decision tree induction to detect artifacts in the neonatal intensive care unit.
Artif. Intell. Medicine, 2000
Proceedings of the AMIA 2000, 2000
First Steps Towards Implementing an International Training Program in Medical Informatics: The Brazil/USA Project.
Proceedings of the AMIA 2000, 2000
Proceedings of the AMIA 2000, 2000
Proceedings of the AMIA 2000, 2000
Proceedings of the AMIA 2000, 2000
Proceedings of the AMIA 2000, 2000
1999
Proceedings of the AMIA 1999, 1999
Proceedings of the AMIA 1999, 1999
Artifact detection in cardiovascular time series monitoring data from preterm infants.
Proceedings of the AMIA 1999, 1999
Proceedings of the AMIA 1999, 1999
1998
LRTree: A Hybrid technique for Classifying Myocardial Infarction Data Containing Unknown Attribute Values.
Proceedings of the Research and Development in Knowledge Discovery and Data Mining, 1998
Proceedings of the AMIA 1998, 1998
Methodology for Computer-Assisted Prediction of Growth Hormone Deficiency in Children.
Proceedings of the AMIA 1998, 1998
Proceedings of the AMIA 1998, 1998
Social equity and access to the World Wide Web and E-mail: implications for design and implementation of medical applications.
Proceedings of the AMIA 1998, 1998
Proceedings of the AMIA 1998, 1998
Proceedings of the AMIA 1998, 1998
Proceedings of the AMIA 1998, 1998
1997
Proceedings of the AMIA 1997, 1997
Proceedings of the AMIA 1997, 1997
1996
Application of Technology: Building National Electronic Medical Record Systems via the World Wide Web.
J. Am. Medical Informatics Assoc., 1996
1995
Artif. Intell. Medicine, 1995
1994
J. Am. Medical Informatics Assoc., 1994
1993
Proceedings of the 13th International Joint Conference on Artificial Intelligence. Chambéry, France, August 28, 1993
Integration of intermittent clinical data with continuous data from bedside monitors.
Proceedings of the Sixth Annual IEEE Symposium on Computer-Based Medical Systems (CBMS'93), 1993
Proceedings of the 11th National Conference on Artificial Intelligence. Washington, 1993