Tom L. Blundell

  • University of Cambridge, Department of Biochemistry, UK

According to our database1, Tom L. Blundell authored at least 49 papers between 1994 and 2021.

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PhD thesis 


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Three Simple Properties Explain Protein Stability Change upon Mutation.
J. Chem. Inf. Model., 2021

A base measure of precision for protein stability predictors: structural sensitivity.
BMC Bioinform., 2021

ProtCHOIR: a tool for proteome-scale generation of homo-oligomers.
Briefings Bioinform., 2021

Utilizing graph machine learning within drug discovery and development.
Briefings Bioinform., 2021

COSMIC Cancer Gene Census 3D database: understanding the impacts of mutations on cancer targets.
Briefings Bioinform., 2021

SARS-CoV-2 3D database: understanding the coronavirus proteome and evaluating possible drug targets.
Briefings Bioinform., 2021

PDBe-KB: a community-driven resource for structural and functional annotations.
Nucleic Acids Res., 2020

Genome3D: integrating a collaborative data pipeline to expand the depth and breadth of consensus protein structure annotation.
Nucleic Acids Res., 2020

ProCarbDB: a database of carbohydrate-binding proteins.
Nucleic Acids Res., 2020

Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design.
J. Chem. Inf. Model., 2020

Systematic Investigation of the Data Set Dependency of Protein Stability Predictors.
J. Chem. Inf. Model., 2020

Utilising Graph Machine Learning within Drug Discovery and Development.
CoRR, 2020

Mabellini: a genome-wide database for understanding the structural proteome and evaluating prospective antimicrobial targets of the emerging pathogen Mycobacterium abscessus.
Database J. Biol. Databases Curation, 2019

SDM: a server for predicting effects of mutations on protein stability.
Nucleic Acids Res., 2017

XSuLT: a web server for structural annotation and representation of sequence-structure alignments.
Nucleic Acids Res., 2017

TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species.
Database J. Biol. Databases Curation, 2017

Platinum: a database of experimentally measured effects of mutations on structurally defined protein-ligand complexes.
Nucleic Acids Res., 2015

Genome3D: exploiting structure to help users understand their sequences.
Nucleic Acids Res., 2015

CHOPIN: a web resource for the structural and functional proteome of <i>Mycobacterium tuberculosis</i>.
Database J. Biol. Databases Curation, 2015

SInCRe - structural interactome computational resource for <i>Mycobacterium tuberculosis</i>.
Database J. Biol. Databases Curation, 2015

DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach.
Nucleic Acids Res., 2014

Does a More Precise Chemical Description of Protein-Ligand Complexes Lead to More Accurate Prediction of Binding Affinity?
J. Chem. Inf. Model., 2014

Polyphony: superposition independent methods for ensemble-based drug discovery.
BMC Bioinform., 2014

mCSM: predicting the effects of mutations in proteins using graph-based signatures.
Bioinform., 2014

Genome3D: a UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH domains.
Nucleic Acids Res., 2013

CREDO: a structural interactomics database for drug discovery.
Database J. Biol. Databases Curation, 2013

TIMBAL v2: update of a database holding small molecules modulating protein-protein interactions.
Database J. Biol. Databases Curation, 2013

USRCAT: real-time ultrafast shape recognition with pharmacophoric constraints.
J. Cheminformatics, 2012

SDM - a server for predicting effects of mutations on protein stability and malfunction.
Nucleic Acids Res., 2011

Comprehensive, atomic-level characterization of structurally characterized protein-protein interactions: the PICCOLO database.
BMC Bioinform., 2011

Ulla: a program for calculating environment-specific amino acid substitution tables.
Bioinform., 2009

BIPA: a database for protein-nucleic acid interaction in 3D structures.
Bioinform., 2009

Discarding Functional Residues from the Substitution Table Improves Predictions of Active Sites within Three-Dimensional Structures.
PLoS Comput. Biol., 2008

Prediction by Graph Theoretic Measures of Structural Effects in Proteins Arising from Non-Synonymous Single Nucleotide Polymorphisms.
PLoS Comput. Biol., 2008

Structural assembly of two-domain proteins by rigid-body docking.
BMC Bioinform., 2008

A Structural Bioinformatics Approach to the Analysis of nonsynonymous Single nucleotide polymorphisms (nsSNPS) and their Relation to Disease.
J. Bioinform. Comput. Biol., 2007

Genome bioinformatic analysis of nonsynonymous SNPs.
BMC Bioinform., 2007

Andante: reducing side-chain rotamer search space during comparative modeling using environment-specific substitution probabilities.
Bioinform., 2007

PROVAT - a versatile tool for Voronoi tessellation analysis of protein structures and complexes.
BMC Bioinform., 2005

CHORAL: a differential geometry approach to the prediction of the cores of protein structures.
Bioinform., 2005

PROVAT: a tool for Voronoi tessellation analysis of protein structures and complexes.
Bioinform., 2005

DDBASE2.0: updated domain database with improved identification of structural domains.
Bioinform., 2003

SCORE: predicting the core of protein models.
Bioinform., 2001

HOMSTRAD: adding sequence information to structure-based alignments of homologous protein families.
Bioinform., 2001

Analysis of conservation and substitutions of secondary structure elements within protein superfamilies.
Bioinform., 2000

Browsing the SLoop database of structurally classified loops connecting elements of protein secondary structure.
Bioinform., 2000

JOY: protein sequence-structure representation and analysis.
Bioinform., 1998

The pattern of common supersecondary structure (motifs) in protein database.
Proceedings of the 28th Annual Hawaii International Conference on System Sciences (HICSS-28), 1995

Structure-based identification and clustering of protein families and superfamilies.
J. Comput. Aided Mol. Des., 1994